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lunarmm
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Fri Mar 28, 2008 7:57 am      Reply with quote
snowqueen,

Longer is not necessarily better. Longer than 1.5mm increases chances of infection as well.

Go with the general chart of recommendations regarding length:

Needle size - used for
0.25mm - baldness, fine wrinkles, gray or thinning hair (and to help topicals penetrate)
0.5mm - alopecia, deeper wrinkles, face rejuvenation
1.0mm - loose elasticity, cellulite, stretch marks, skin pigmentation
1.5mm - acne scars, large pores, deep wrinkles, anti-aging, chicken pock scars
2.0mm - surgical scars, stretch marks, deep pitted acne
2.5mm - deep scars, body lifting, severe acne

Needle Length---Max Penetration
0.25 mm --------0.07 mm
0.50 mm --------0.30 mm
1.00 mm --------0.70 mm
1.50 mm --------1.30 mm
2.20 mm --------1.50 mm

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ScotsLass
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Tue Apr 01, 2008 1:45 am      Reply with quote
skincarefreak wrote:
...Could anyone tell me how you sterilize it? Should I sterilize before using it? Thanks

Though your roller technically arrives sterilized, you really ought to rinse it with a anti-bacterial/sterilization solution before you roll your face for the first time, and especially AFTER each rolling session (rather than using water alone). As a general practice, I recommend a 20 minute soak in Hydrogen Peroxide followed by a good rinse under hot running water for a fast and cost-effective method of cleaning your roller before your first roll (then repeat this again after you've finished).

For those who are prepping their faces with topicals (actives and/or serums) BEFORE or DURING a rolling session, another effective method of sterilizing your roller from the debris that will collect on the needles is to use *Denture Tablets*. Denture tablets are not only anti-bacterial agents, they are enzyme cleansers which means they can break down skincare serums & creams as well as fatty deposits that attach to the needles from your skin cells. Simply add one tablet to a half cup of warm water and soak the roller head for 20-30 minutes, then rinse well under running water before air drying. www.dermroller.com/mts-protocols.html

A soft toothbrush is also very useful for gently removing any remaining debris on the needles, however, this may not be necessary at all after a good soak with a denture tablet.

Denture tablets are not only very effective, they are also much cheaper compared to other enzyme cleansers being sold specifically for dermarollers. Here is a product that initially caught my eye before I discovered that denture tablets will do the exact same thing - www.oniskai.com/shop/product_info.php?products_id=107&osCsid=2f95219ae16ffd395dce0996f7928c4a

Thanks to Readers Digest I've discovered that Denture Tablets have many other extraordinary uses; check out this link for more interesting tips. Smile www.rd.com/tools-and-quizzes/extraordinary-uses/extraordinary-uses-for-denture-tablets/article23830.html

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ScotsLass
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Tue Apr 01, 2008 5:45 pm      Reply with quote
anomaly wrote:
Cadia wrote:
Hello Nan! Smile

Glad you joined us!

A lot of people feel the need for numbing cream so you are not alone there. The cooling gel for sunburn might do just fine, but in case you don't think it helps enough, you could try Emla as that seems to be what many people prefere. Ice cubes are also helping.

At www.microneedle.com they suggest a solution that contains benzocaine (20%), lidocaine (4%), teracaine (2%), pramoxine HCI (1%). I use a home-made mix of benzocaine (20%) and lidocaine (2,5%) which works fine for my sensitive mouth area. Cleanse with a sponge after checking anesthesia and you're good to roll Very Happy

I'm sure you'll have great results. Just take your time and hang in there Smile

Oh, and good luck tonight!
Hope to hear more about your experiences soon!

Cadia

I read in "health" magazine that two young girls (20s) died from topical anesthesia... one was going in for laser hair removal and the other i forgot. And they said that people have been hospitalized from OTC numbing creams. Just a heads up... Reading that scared me. But they put it on a large area and wrapped it in a wrap. Still, I'm a hypochondriac, so I'd rather have pain than use that stuff. lol

Anomaly - Thank you for raising an important point about the potential dangers of using medicated numbing topicals. Before I even ordered the Tridocaine Gel (that I like very much and recommended in an earlier post), I personally called the Pharmacist who compounds this product (back in February) and asked if it was suitable to use with derma rollers. I was told it is perfectly safe as Tridocaine is the number one gel they sell to Tattoo artists, who are essentially 'needling' the skin in much the same way that derma rolling does. I suggest everyone talk to their Pharmacist before they use any topical analgeics just to be on the safe side.

From what I have gathered, if there are any *warnings* at all about using OTC numbing agents they would be the following:

1) DO NOT cover a topical analgesic that contains Benzocaine with Cling Wrap or Saran Wrap as this can be VERY dangerous if too much of this specific medication is delivered into your blood stream for a prolonged period of time. And this is exactly what Saran/Cling Wrap applied on top of a numbing cream can do; it behaves as an occlusive dressing which means it prevents air from causing the topical agent to become inert, thereby prolonging the numbing properties of the product on your skin and in your blood stream. An additional definition of how occlusion works is provided here - http://wiki.bmezine.com/index.php/Occlusive_Bandage. The use of 'occlusive bandages' is approved with Emla Cream, however, this does NOT mean it is approved for such use with OTHER topcial analgesics (such as Xylocaine and especially not with Benzocaine!!! Shock ). In fact, there is much evidence to support that you should never use saran wrap on top of Benzocaine at all. Here is a very good article from Healthline that discusses what you should know about using Benzocaine as a topical analgesic. www.healthline.com/multumcontent/benzocaine-topical

2) As soon as the area you want to roll is numb from any topical analgesic, use a damp cloth and wipe your skin clean BEFORE you begin to roll so that you are NOT pushing the numbing gel deeper into the dermal layers with your roller (which in turn delivers it further into your blood stream).

I am very light handed when I use the Tridocaine Gel and apply it primarily to area's that are very sensitive for me. What I love about this product is that it is only on my skin for 15 minutes before I rinse my face prior to a rolling session, and that it generally wears off within 15 to 20 minutes of my skin becoming fully numb. This means my numbing 'downtime' is so much less involved and cumbersome compared to the Emla Cream/Occlusive procedure. I have not had any side effects or problems with Tridocaine Gel either.

So for anyone thinking of numbing larger areas of their body in order to use longer derma rollers (ie/, the 2.0 mm and 2.5 mm models), you should be VERY careful about how much analgesic you use and NEVER be tempted to use saran wrap on top of anything other than Emla Cream, unless you have it on good authority that it is okay to do so.

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skincarefreak
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Sat Apr 05, 2008 4:33 pm      Reply with quote
anya wrote:
I hope there's room for one more "roller girl" at this party Very Happy. You girls have been such an inspiration, not only with encouragement, but with the wealth of information you've given!!
I finally got delivery of my 1.5 cm Dr. Roller after 3 weeks of assaulting the postman every morning Rolling Eyes

Soooo, I'm about to take the big leap, but had a question re. spider veins. I have one that's about 1" long on my chin and I'm wondering if I should roll it or avoid it Confused I see some of you have had success with broken caps..., but I'm nervous about "bursting" the vein and having blood everywhere Laughing Any ideas?

TIA.

Anya


Hi Anya,

I don't have answer for you, but I did want to welcome to you to the thread!
Cadia
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Sun Apr 06, 2008 1:13 pm      Reply with quote
anya wrote:
I hope there's room for one more "roller girl" at this party Very Happy. You girls have been such an inspiration, not only with encouragement, but with the wealth of information you've given!!
I finally got delivery of my 1.5 cm Dr. Roller after 3 weeks of assaulting the postman every morning Rolling Eyes

Soooo, I'm about to take the big leap, but had a question re. spider veins. I have one that's about 1" long on my chin and I'm wondering if I should roll it or avoid it Confused I see some of you have had success with broken caps..., but I'm nervous about "bursting" the vein and having blood everywhere Laughing Any ideas?

TIA.

Anya


Hi Anya Smile

I missed your post, but I'm glad you joined us! Very Happy Thank you so much for the comment about assaulting the postman, it made me laugh and really brightened my rainy day here Laughing

I'm not of much use when it comes to the vein issue, but it's an interesting aspect that I would also like to hear more about.

Please let us know how your rolling goes.

Cadia Smile
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Sat Apr 12, 2008 3:22 am      Reply with quote
catski wrote:
ScotLass thankyou for that info. So yes, I will go slow. I didnt have oozing, use cp's or get bloody. Thankfully! I'll leave it a couple of weeks till I roll there again, and only then if I feel I need to. The skin there is already much nicer, after just two rolls. It was getting a wee bit crepey. Confused Confused Confused

The GP used a freeze device which actually is more commonly used for wart removal. She held it on for 60 seconds, and it was a burny feeling, but extremely bearable. I had two rounds of it and that's it. Fantastic, eh?

I have, btw, been trying the caudalie beauty elixir which I was told is great for sun damage. pfffft, is all I can say on that one.. Wink


Hey Catski - Glad to have helped in any way. Smile If your chest skin is starting to look better now, then you might want to persevere with all 6 roller sessions even if they have to be spaced out a bit. Once you stop rolling this area after the 6 treatments, you should see significant results begin to emerge from 90 days and onwards.

I can't wait to hear how you make out with the NIA24 Decolletage cream, as I am confident that any results you gain from this product will arrive that much faster thanks to your derma roller treatments.

Thanks for explaining how your GP zapped away your sun damage. It sounds so easy and effortless that I am going to look into it myself and see if a Derm can do the same thing for me. Cool

I'm also glad to scratch off another product that isn't worth trying! Thanks for mentioning how ineffective the Caudalie Beauty Elixir is for hyperpigmention! Rolling Eyes

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sharky
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Mon Apr 14, 2008 2:39 pm      Reply with quote
I'm sure that the roller works now for caps after three rolls my chin cap is definately less apparent. I was a bit worried at first because it looked darker an fuzzier after the first roll but I will not be hesitant to roll at cap again.

Hi to all the new rollers! have fun it works.
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Fri Apr 18, 2008 3:19 am      Reply with quote
catski wrote:
How long does a roller last? How do we know if we need a new roller?

I think this really depends on the brand you own and where you are using your roller (i.e., face alone or face and body). The skin on your body is much thicker than the skin on your face, neck (and to a degree decolletage). So the needles do wear down somewhat faster when you're rolling all over, versus the face alone.

For those who have the stainless-steel medical grade rollers, I read that you should be able to use these models for a good 6 months (with proper care) before they need to be replaced. This means you should get around 180 rolling sessions, plus or minus, out of these rollers.

If you feel you need to push harder with your roller and/or notice additional blood spots on your face after a roll (and you've used your roller multiple times), I would consider a new one. There is no hard and fast rule about gauging the dullness of the needles, so it sounds as if it all boils down to quality and the number of proposed roles set forth by the manufacturer.

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Fri Apr 18, 2008 11:42 am      Reply with quote
sherryf13500 wrote:
My goal is to get rid of or lessen the lines around my lips and sag around my jaw.

I bought my roller on ebay from dermaroller. It is a dr. roller? 1.5

I have had it a total of 2 weeks. I used it the first week 3 times. Three treatments. The second week after reading the steam of information here, I only rolled once.

So that is where I am
My routine is:
AM
Cleanse face
Vit C - 30 min before all the rest.
Matrixyl 3000
HA
Emu oil
sunscreen

PM
Cleanse face
Pat Dry
CP - Just plain CP (first strength recommended for new users)
after 30 min.
Emu oil and HA, Matrixyl 3000

Sleep!

Okay Sherry, this is just an idea, but I would apply your Matrixyl 3000 before you roll with your 1.5 mm during your weekly sessions. Matrixyl 3000 is supposed to dramatically boost the synthesis of Collagen I, III, and IV, which is IDEAL for what you are trying to achieve with the roller! Okay, not only that, but Matrixyl 3000 improves moisture retention and tightens and firms your skin. Here is an inspiring excerpt that really has me wondering how much better your results will be with this peptide complex once it is delivered deeper into your skin - WOW! Can't wait to find out! Wink

Quote:
Matrixyl 3000 (Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7)is formerly known as Palmitoyl Tetrapeptide-3. This peptide has an anti-wrinkling and lifting effect. It's two components, Pal-GHK and Pal-GQPR, act in synergy to restore and maintain skin's youthful appearance. With regular use of Matrixyl 3000, it is possible to obtain up to 45% less wrinkling in just two months.

By pushing the Matrixyl 3000 into your skin with the roller you are delivering the serum significantly deeper than if you were to apply the serum on it's own after a treatment. Once you've finished your session, I would wait until several hours have has passed or the next day and then apply a good application of Emu Oil (use a good moisturizing cream to tie you over to the next day if necessary, but not HA on it's own as this can be too drying after a moderate roll). The reason I am NOT suggesting you apply Emu Oil while the holes are still open (post-roll) is because emu oil is a known anti-inflammatory, and you do not want to use any kind of anti-inflammatory products while you are performing this 6 week treatment plan (this is more important while the holes are open).

There are two reasons for this; the first is that inflammation during the wound-healing phase is important as it helps the collagen production cycle yield better results; the second reason is that Emu Oil contains EFA's and these can alter how your blood clots. This in turn can cause bruising to develop when it could have been avoided all together. EFA's also include Omega Supplements, so it is suggested that you stop taking these supplements as well during this period. Aspirin is another anti-coagulant, so cease taking it too while you're working through your 6 treatments. Once the 6 week program is over, you can resume regular use of Emu Oil, Omega Supplements and Aspirin.

I would also highly recommend you think about buying another smaller roller to continue with once you retire the 1.5 mm size after your first 6 week cycle ends. Both rollers will last a good while so the investment is well worth it, IMO. A smaller roller will allow you to keep focusing on the upper layers of your skin with your topicals, which can only produce additional results. And all I can say to that is ROCK 'N ROLL ON, BABY!!! Image

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Sat Apr 19, 2008 9:53 am      Reply with quote
Keliu wrote:
I recently emailed the Nova Clinic to find out the recommended protocol for using the 1.5mm roller. I asked them whether rolling every week for six weeks and then taking a break for 90 days was appropriate. This was their reply:

There are several ways, your method below is one.

Another way is to use it every 2nd day, or 5 days out of 7. Another is to use it more firmly with an anesthetic gel once a week or once a
month.

See what fits in with your life style, all methods will work well for anti-aging.

Regards Nova Clinic


So according to their response, it would seem that it is not absolutely necessary to take a break from rolling.


No, you are right, there's absolutely no need for a break. Someone has gotten the whole concept wrong.

Professional rolling (like you said in an earlier post) is very hard and need about a week to heal. This does not mean that it cannot be used more often if the skin is healing sooner. You should just not use it on wounded skin or with active acne.

The six treatments, then a break comes from the same fact that you look horrible for about a week after professional rolling. That makes it's a big deal to limit the treatments. Six professional sessions are enough to see a big change and enough to fulfill many people's wishes so they normally stop there for a while in order to see if additional treatments are needed.

Another point is that to compare 6 professional sessions with 6 at home sessions doesn't make sense. It's two completely different treatments. The professional rolling does not leave any skin looking normal. The pictures I linked to earlier illustrate the roughness of the treatment.

There's also misleading to say that it's recommended to have a professional treatment once a week for six weeks. The recommended interval is from one week to one month. The more you want to fix, the shorter the break.

And just for the record - rolling does not break down any collagen. If that was the case, you would only have a single roller session. Otherwise the last five of the six treatments would only break down what the others had done.

Rolling is based on exploiting the skin's wound healing process. This is explained very good in one of the articles I've posted earlier. Not the easiest reading, but once one gets the basic principles right, the mystery about rolling and how it works are solved. It's an extremely simple, safe and efficient routine! Smile
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Sat Apr 19, 2008 6:24 pm      Reply with quote
In regard to the professional needling treatments given by doctors: Dr. Des Fernandes (the pioneer of skin needling) actually uses a tattoo gun to needle his patients - this is done under sedation. As I've said before, I don't think it makes sense to compare professional treatments with home treatments - they are so much more invasive.

In regard to topicals used with needling: Dr. Fernandes recommends using Vitamins A, C and E. Interestingly, he says that he will not needle someone unless they have been using Vitamin A (Retin-A) for three months beforehand. He stresses it is very important to use Retin-A after needling.

There are lots of articles written by Dr. Fernandes about CIT (collagen induction therapy) available on the web. Just google his name or have a look on the Environ skin care sites.

Environ also sell skin rollers for home use. This is their recommendation for home treatment:

TREATMENT

The treatment time can range from 5-20 minutes depending on the speed, accuracy and density.

The treatment should be repeated at home between two to seven times a week. The more frequent the treatment, the better the result. The instrument cannot be "over-used" as the needles will remain sharp for a prolonged time.

If the skin feels sensitive after a treatment, it should not be repeated until the skin feels comfortable. The tiny holes in the horny layer are sealed within a day.
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Sun Apr 20, 2008 9:50 am      Reply with quote
This is the best read I've found so far that explains the process in great detail:

http://www.dermogenesis.com/roll-cit/Clinics_of_N_Am_2005.pdf

The most detailed section of the document in regard to collagen induction and how it works after PCI (needling):

Technique of percutaneous collagen induction

The skin is routinely prepared by using topical vitamin A and C and antioxidants for at least 3 weeks, but preferably for 3 months if the skin is very sun damaged. If the stratum corneum is thickened and rough, a series of mild TCA peels (2.5%–5% TCA in a special gel formulation) will get the surface of the skin prepared for needling and maximize the result.

Under topical, local, or general anesthesia, the skin is closely punctured with the special tool that consists of a rolling barrel with needles at regular intervals. By rolling backward and forward with some pressure in various directions one can achieve an even distribution of the holes. The skin should be needled as densely as possible. Usually, as the needle holes get too close to each other, the needle ‘‘slips’’ into an established hole and so it seems impossible to over treat the skin. For very superficial small scars, I use a simple tattoo-artist’s gun as described by Camirand and Doucet. When using the tattooartist’s machine, one has to be very careful not to overtreat an area because the skin can then be damaged because the needles plough their way through the skin and may remove the epidermis. The needles penetrate through the epidermis but do not remove it, so the epidermis is only punctured and will rapidly heal. The needle seems to divide cells from each other rather than cutting through the cells so that many cells are spared.

Because the needles are set in a roller, the needle initially penetrates at an angle and then goes deeper as the roller turns. Finally the needle is extracted at the converse angle and therefore the tracts are curved, reflecting the path of the needle as it rolls into and then out of the skin. The epidermis and particularly the stratum corneum remain intact, except for these tiny holes, which are about four cells in diameter. The needles penetrate about 1.5 to 2 mm into the dermis. Naturally, the skin bleeds for a short time, but that soon stops. The skin develops multiple microbruises in the dermis that initiate the complex cascade of growth factors that eventually results in collagen production. After the bleeding stops, there is a serous ooze that has to be removed from the surface of the skin. Wet gauze swabs soak up most of the serous ooze. As the skin swells, the holes are closed, the edges of the epidermis are approximated, and the ooze stops. Noxious chemicals, however, may still penetrate the skin, so only safe molecules should be used topically. After this serous leak has stopped, the skin is washed thoroughly and then covered with vitamin A, C, and E oil or cream (do not use ascorbic acid). The patient is warned that they will look terribly red and bruised, and they are encouraged to shower within a few hours of the procedure, when they return home.

Why percutaneous collagen induction works

PCI results from the natural response to wounding of the skin, even though the wound is minute and mainly subcutaneous. A single needle prick through the skin would cause an invisible response. It is necessary to understand that when the needle penetrates into the skin, this injury, minute as it might seem, causes some localized damage and bleeding by rupturing fine blood vessels. Platelets are automatically released and the normal process of inflammation
commences, even though the wound is miniscule. A completely different picture emerges when thousands or tens of thousands of fine pricks are placed close to each other and one gets a field effect, because the bleeding is virtually confluent.

This promotes the normal post-traumatic release of growth factors and infiltration of fibroblasts. This reaction is automatic and produces a surge of activity that inevitably leads to the fibroblasts being ‘‘instructed’’ to produce more collagen and elastin. The collagen is laid down in the upper dermis just below the basal layer of the epidermis. It now becomes important to understand the process of inflammation in detail. An excellent reference on this topic is the chapter ‘‘Wound Healing’’ by Falabela and Falanga in The Biology of the Skin. There are three phases in wound healing:

Phase I: inflammation, which starts immediately after the injury

Phase II: proliferation (tissue formation), which starts after about 5 days and lasts about 8 weeks

Phase III: tissue remodeling, from 8 weeks to about 1 year


Phase I: initial injury
The inflammation phase starts when the needles prick the skin and rupture blood vessels and blood cells and serum gets into the surrounding tissue. Platelets are important in causing clotting and releasing chemotactic factors, which cause an invasion of other platelets, leucocytes, and fibroblasts. The leucocytes, particularly neutrophils, then act on the damaged tissue to remove debris and kill bacteria. After the platelets have been activated by exposure to thrombin and collagen, they release numerous cytokines. This process involves a complex concatenation of numerous factors that are important in (1) controlling the formation of a clot (eg, fibrinogen, fibronectin, von Willebrand factor, thrombospondin, ADP, and thromboxane); (2) increasing vascular permeability, which then allows the neutrophils to pass through the vessel walls and enter the damaged area; (3) attracting neutrophils and monocytes; and (4) recruiting fibroblasts into the wounded area.

Of special interest in understanding the action of PCI are the following:

1. Fibroblast growth factor: promotes not only fibroblast proliferation but also epidermal proliferation and stimulates the production of new blood vessels. Vitamin A is an essential regulator of differentiation of fibroblasts and keratinocytes so adequate doses in the tissues are required at this stage. In anticipation of the interrupted blood supply, it should be ensured that the highest-possible normal levels of vitamin A are stored in the skin before PCI.

2. Platelet-derived growth factor: chemotactic for fibroblasts and promotes their proliferation, meaning that more collagen and elastin will be made. The need for vitamin C at this stage becomes crucial because without adequate
levels of this vitamin, proline and lysine cannot be incorporated into collagen and the strands will then be defective.

3. Transforming growth factor a (TGF-a): facilitates re-epithelialization. In the case of PCI, re-epithelialization is not an important action.

4. Transforming growth factor b (TGF-b): a powerful chemotactic agent for fibroblasts that migrate into the wound about 48 hours after injury and start producing collagen types I and III, elastin, glycoseaminoglycans, and proteoglycans. Collagen type III is the dominant form of collagen in the early wound-healing phase. Again, this action is heavily dependent on adequate doses of vitamin C. At the same time, TGF-b inhibits proteases that break down the intercellular matrix.

5. Connective tissue activating peptide III: also promotes the production of intercellular matrix. Fibroblasts migrate into the area, and this surge of activity inevitably leads to the production of more collagen and more elastin. Vitamin A and C again are important mediators of this action.

6. Neutrophil activating peptide-2: has a chemotactic effect for neutrophils that then migrate into the wounded area. Neutrophils are important for killing bacteria and helping to debride tissue but, in the case of PCI, their main action is the release of cytokines that enhance the effects of the platelet cytokines (eg, plateletderived growth factor and connective tissue growth factor).

Phase II: the period for tissue proliferation
As time passes, probably about 5 days in the case of PCI, neutrophils are replaced by monocytes. The monocytes differentiate into macrophages and phagocytose the decaying neutrophils. They are very important for the later healing phases because they remove cellular debris and release several growth factors including platelet-derived growth factor, fibroblast growth factor, TGF-b, and TGF-a, which stimulate the migration and proliferation of fibroblasts and the production and modulation of extracellular matrix.

With PCI, there is only extravasated blood and very little connective tissue damage to be dealt with. Bacterial infection is rare, but it has been noticed that when the needled area gets infected, greater smoothing of skin may occur, probably due to a heightened growth factor response. In standard wounds, the inflammatory phase ends after about 5 to 6 days, as proliferation and tissue formation ensue. In these cases, the main cell is the keratinocyte. Keratinocytes change in morphology and become mobile to cover the gap in the basement membrane. The changes include retraction of tonofilaments and the dissolution of desmosomes and hemidesmosomes so that the cells can migrate. Peripheral cytoplasmic actin filaments also are developed that ‘‘pull’’ keratinocytes together to close the wound. These actin filaments, however, are not an important factor in PCI because re-epithelialization, or the closure of the needle holes, occurs within a few hours after needling because the gap is so small.

Disruption of the basement membrane by PCI destroys the lamina lucida and brings basal keratinocytes into direct contact with the underlying collagen, which inactivates laminin and stimulates keratinocyte migration. When the keratinocytes have joined together, they start producing all the components to re-establish the basement membrane with laminin and collagen types IVand VII. A day or two after PCI, the keratinocytes start proliferating and act more in thickening the epidermis than in closing the defect.

Initially after PCI, the disruption of the blood vessels causes a moderate amount of hypoxia. The low oxygen tension stimulates the fibroblast to produce more TGF-b, platelet-derived growth factor, and endothelial growth factor. Procollagen mRNA also is upregulated, but this cannot cause collagen formation because oxygen is required (which only occurs when re-vascularization occurs). Collagen type III is the dominant form of collagen in the early wound-healing phase and becomes maximal 5 to 7 days after injury. The longer the initial phase, the greater the production of collagen type III. If the injury extends deeper than the adnexal structures, then myofibroblasts may contract the wound considerably. Although the injury in skin needling extends deeper than the adnexal structures, because the epithelial wounds are simply cleft, myofibroblast wound contraction may not play a part in the healing.

A number of proteins and enzymes are important for fibroplasia and angiogenesis that develop at the same time. Anoxia, TGF-b, and fibroblast growth factor and other growth factors play an important part in angiogenesis. Fibroblasts release insulinlike growth factor that is an important stimulant for proliferation of fibroblasts themselves and endothelial cells. Insulinlike growth factor is essential in neovascularisation. Insulinlike growth factor or somatomedin-C also is one of the main active agents for growth hormone. Integrins facilitate the interaction of the fibroblasts, endothelial cells, and keratinocytes.

Phase III – the process of tissue remodeling
Tissue remodeling continues for months after the injury and is mainly done by the fibroblasts. By the fifth day after injury, the fibronectin matrix is laid down along the axis in which fibroblasts are aligned and in which collagen will be laid down. TGF-b and other growth factors play an important part in the formation of this matrix. Collagen type III is laid down in the upper dermis just below the basal layer of the epidermis. Collagen type III is gradually replaced by collagen type I over a period of a year or more, which gives increased tensile strength. The matrix metalloproteinases (MMPs) are essential for the conversion process. The various MMPs are generally classed as MMP-1 (collagenases), MMP-2 (gelatinases), and MMP-3 (stromelysins).

Care of the skin after percutaneous collagen Induction

Immediately after the treatment, the skin looks bruised, but bleeding is minimal and there is only a small ooze of serum that soon stops. The author recommends soaking the skin with saline swabs for an hour or two and then cleaning the skin thoroughly with a Tea Tree Oil–based cleanser. The patient is encouraged to use topical vitamin A and vitamin C as a cream or an oil to promote better healing and greater production of collagen. The addition of peptides like palmitoyl pentapeptide could possibly ensure even better results. At home, the patient should stand under a shower for a long time, allowing the water to soak into the surface of the skin. Bathing is discouraged because of potential contamination from drains and plugs.

Patients should be reminded to use only tepid water because the skin will be more sensitive to heat. While the water is running over the face or body, the patient should gently massage the treated skin until all serum, blood, or oil is removed. The importance of a thorough but gentle washing of the skin, a few hours after the procedure, cannot be stressed enough. The skin will feel tight and may look uncomfortable in a few cases. Most patients say that the skin is a little sensitive but the major complaint is about the bruising and swelling. The following day, the skin looks less dramatic and by day 4 or 5, the skin has returned to a moderate pink flush, which can easily be concealed with makeup.

Men usually seem to heal faster and are less bruised than women. From day 3 or 4 onward, iontophoresis and low-frequency sonophoresis of vitamin A and C could maximize the induction of healthy collagen. Iontophoresis also tends to reduce the swelling of the skin, which also helps the patient look better sooner. Low-frequency sonophoresis can be used alone without iontophoresis to enhance penetration of palmitoyl pentapeptide or other peptides (eg, palmitoyl hexapeptide, copper peptides, and so forth), which also may increase the creation of healthy collagen and elastin.

After the skin has been needled, it becomes easier to penetrate, and much higher doses of vitamin A become available in the depth of the skin. Higher doses of vitamin A may cause a retinoid reaction even though the milder forms of Vitamin A (eg, retinyl palmitate) are being used. This reaction will aggravate the pink flush of the skin and also cause dry, flaky skin. Needling may cause some slight roughness of the skin surface for a few days, and this condition is definitely worse when topical vitamin A is used. The clinician should ignore this and urge the patient to continue using the topical vitamin A. Patients usually anticipate that their skin will get red and do not complain much about that but become concerned about the dryness. It should be remembered that the skin has lost the important barrier function of keeping the water inside the skin. Until this barrier function is restored completely after a few days, the skin will feel dry. A hydrating cream or even petrolatum can be used to soothe the dry sensation.

When the patient has not cleaned the skin thoroughly, a fine scab may form on the surface. The formation of scabs should be discouraged because they may cause obstruction and the development of simple milia or tiny pustules. Milia are uncommon but when they occur, they should be treated by pricking and draining. Tiny pustules are more common and usually found in patients treated for acne scars. It is important to open them early and make sure that the skin has been cleaned thoroughly and that there is no serous residue on the surface. When the pustules are allowed to dry on the skin, they will form thin scabs that effectively prevent the penetration of the vitamins necessary for a successful treatment.

The patient should avoid direct sun exposure for at least 10 days if possible and use a broad-brimmed hat or scarf to protect the facial skin. Patients may shocked when they look in the mirror, but this procedure is a far less shocking experience than laser resurfacing. The treatment can be repeated a month later, but the best interval between treatments is presently unknown. If a clinician intends to achieve a smoothing comparable to a laser resurfacing, then depending on the original state, a patient may require three or even four treatments. The results that are achieved are not temporary but endure for many years. Again, it should be emphasized that this progress is utterly dependent on adequate nutrition for the skin.

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Mon Apr 28, 2008 10:52 am      Reply with quote
Hello again!

Catski did pm me asking me few questions. I thought it would be nice to share my reply with you all:

Quote:
I have worked with 2mm and 3mm deep. I have the MTS professional grade rollers.
What I did to avoid infection was to use topical iodine before starting rolling and, sometimes, after applying the tretoin, I used a bit of neem oil or tea tree oil(not the essential oil forms, but the cold pressed ones. They both have antiseptic properties. She never got an infection or anything similar. It is my personal opinion than our skin can really get over a little infection from a little puncture, but what I have been focused on avoiding is to spread any existing bacteria already existing in our skin or in the roller by the process itself.
Iodine is safe and is what is mostly used in hospitals topically before they cut the skin for any intervention.
Everything else is already posted.

My poor sister has been my guinea pig to target issues that I do not have.
I have used her too to test cupping to reduce cellulite, and she is so happy that now she does it by herself.
It is the minimum I can do for her considering she is going to a difficult divorce and now has to face life alone and with pretty much nothing but her two hands....

I hope this helps!

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Mon Apr 28, 2008 1:18 pm      Reply with quote
I have read at earthclinic there is some type of clear iodine to not get stained: http://www.earthclinic.com/Remedies/iodine.html
They say:
Quote:
Nita, from St Pete, Fl: Iodine definitely works for me, however, I find it best to use the clear "decolorized" iodine, available at most drugstores. I paint it on the inside of the wrists (where the veins are closest to the skin) and on the sides of the throat.

We found "decolorized iodine" at Walmart last summer "


I have not used clear iodine, but found that the regular one did not stain that much, in fact I would say it was very easy to clean. I guess it might depend on what brand you use.

Just give it a try and see how it works if you want to roll deeper and prevent infections.

Edited to add: just google decolorized iodine and you will be able to find the product and all the info available.
Wink
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Mon May 05, 2008 3:51 pm      Reply with quote
Sharky, I roll and do light therapy, and I have a Quasar SP, which I love. I started with the Baby Quasar and upgraded to the SP so as to have a bigger treatment head.

However, SP is a bit pricey, and more than many of us want to spend. If I were buying on more of a budget I'd probably go with ProLight. As it is I'm strongly considering buying an amber ProLight to complement the reds and infrareds of the SP. There are many threads in the DIY forum on the various LED's available, and with all the chatter about light therapy lately I believe all the good threads are on the first or second page. It's there you should go for info, since this is the Dermaroller thread.

One thing...the consensus seems to be that a bit of temporary irritation and inflammation is desirable when rolling, so you don't want to do anything that's going to immediately "calm" the irritation that rolling provokes. This includes light therapy, whatever you decide to buy. Myself, I'm going to wait at least a couple of days before "lighting up" after rolling. Wink
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Tue May 06, 2008 4:41 pm      Reply with quote
One thing that has occurred to me as a fairly experienced roller (several months now), is that this does not have to as brutal a process as some people seem to be seeing it.

It is easy to start slow, go light, just do a patch. You can modify the discomfort.

For example lately I have been really busy and had trouble fitting rolling in. I usually use ice as my pain management..but even that adds to the time involved. So what I am doing is not icing, and just doing small patches, over many nights. I actually like doing it this way. I can manage the redness, And I think I can modify the way I roll ie how hard, how much depending on the area.

I really do beleive this can be a "progressive" treatment. I don't think you need the lobster look to be successful.

As far as topicals, I find a small squirt of Vit C into my HA is wonderful. No stinging, no peelies. Perfect.

rebecca

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Thu May 15, 2008 4:10 pm      Reply with quote
ruk1 wrote:
Where does everyone buy your dermaroller? What brand is the best one?


I purchased my first roller (1.0mm) from the Nova Clinic for $105.00.

Last month I purchased my 0.5mm & 1.5mm rollers from this site: http://www.dermarollers.us/ They have a good sale going on now (and free shipping), plus if you use coupon code 248f3 during check out, you receive another 20% off your roller. Today, May 15th, is the last day that coupon code is valid. I'm very pleased with both brands as the needles are very sharp and fine.

Jen
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Sun May 18, 2008 7:52 am      Reply with quote
Hi Scots. I did six of these very interventional rolls. Sometimes I spaced them apart by ten days or two weeks, to allow the skin to recover fully. I was using the 1.5.

I applied supercop2 afterward, too, sometimes pretty soon afterward ( really severely ouchy) and sometimes not untill the day after rolling.

It was dramatic, in terms of redness, swelling, hurtiness.And it was also dramatic in terms of really huge improvement.

What were previously fuschia 'runs in your stockings' deep marks, are now very pale, closer to the surface. And the whole area has better quality skin. It was previously ruined skin that was crepey and overstretched. ( I feel I should say that I got such appalling stretchmarks probably because I was depressed when pregnant and I ate like a horse and applied no oils to my body.. Crying or Very sad )

The skin now isnt noticeably ruined, from a distance. But it isnt even and smooth. So I'm planning to do another round of rolling in the autumn, and I'm wondering about getting a longer needled roller, as Zenity did for her sister.
I'm beginning to think that I maybe able to entirely undo the damage. It would not only lift my spirits hugely from the aesthetic point of view, but also make me feel I'd made it up to myself for the way I neglected myself when I was pregnant.
So it feels a wonderfully creative proccess. I'm very amazed by it.
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Sat May 24, 2008 11:39 am      Reply with quote
Here are some additional roller articles for people like me who read things to death before trying them. Very Happy I pulled together a list for another forum, so please overlook any already duplicated in this thread.


Page 8 contains CIT frequency recommendations based on skin condition:
http://www.euromeditravel.com/doc/additional_info.pdf


Some results pics and detailed directions on how to do a roll, including frequency of usage for the .2mm Environ home care roller:
http://www.beautymagonline.com/pages/environ_rollcit.htm


An overview of the process from Dr. Des Fernandes, including some frequency recommendations:
http://www.vivida.co.za/db_files/16_IIAA_newsletter.pdf


Some results photos from a Boston doctor:
http://www.bostoncentreaestheticmedicine.com/collageninduction.html


A Miami doctor's webpage, with links to a video of him performing the procedure:
http://www.drbustillo.com/roll-cit.htm


The Dermaroller blog where I asked Horst Liebl about needle length, and his reply:
http://dermaroller.wordpress.com/2008/05/17/question-about-collagen-function/


The Dermaroller blog with a question and answer on treatment frequency:
http://dermaroller.wordpress.com/2008/04/25/question-about-treatment-intervals/


STIMULATION OF CELL GROWTH by Horst Liebl
http://www.dermaroller.de/us/science/abstract-reflections.html


Electrical Signals Control Wound Healing (dermarollers generate electrical charges)
http://www.dermaroller.de/images/stories/Findings.pdf


Percutanous Delivery By Dr. K. Anastassakis May 2005
http://www.dermaroller.de/us/science/percutanous-delivery.html


Collagen Induction Therapy in Mouse ( IPL vs. Micro-needling )
http://www.clinicalresolution.com/main/MTS-ueljihospital.pdf#pagemode=thumbs&page=1


Skin Needling - A New Treatment for Scars and Lines
http://www.mesotherapyworldwide.com/images/pdf/Skin%20Needling%20for%20Doctors_MW.pdf


Percutaneous Collagen Induction Therapy: An Alternative Treatment for Scars, Wrinkles, and Skin Laxity
http://www.acaciadermacare.com/upload/docs/PCI%20-%20Plastic%20Surgery%20Journal%20-%20April%202008.pdf

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Sun Jun 01, 2008 11:52 am      Reply with quote
This next one has recommended protocols for using the MTS Roller...the domain expired so I am including the info from the cached page here. (I also included the needle lengths for the various models mentioned)

MTS-Roller Model: CR2 (0.2mm)
MTS-Roller Model: CR3 (0.3mm)
MTS-Roller Model: CR10 (1mm)
MTS-Roller Model: CR20 (2mm)


Quote:


PROTOCOLS For MTS Roller™
MEDICAL and PERSONAL USE


Summary
The common goal of most skin treatment modalities is the reduction of wrinkles and scars and depressions of the skin. MTS Roller™ is a low-cost/high results skin treatment alternative for ablatives like laser resurfacing, derma/microbrasion, and chemical peeling.

Description
MTS Roller™ uses 200 very fine needles to pierce the epidermis thereby stimulating collagen formation. The resulting ‘micro-channel effect’ also helps to infuse vitamin creams, serums, and other topical applications thereby increasing their effectiveness.

The recommended program: once a month for a total of six months using a wash, one treatment roller (MTS Roller model CR5 and up), a topical anesthetic (e.g., benzocaine, lidocaine, tetracaine, pramoxine HCI), two topical esthetics (e.g., peptide, retinol, collagen), a soothing mask, moisturizer, sun block (SPF 30). Clinicians may also use MTS Roller model CR2 for application of the anesthetic. Other treatment options include ultrasound, Ionto, topical skin nutrients, with follow up treatment of microdermabrasion to help smooth the surface and enhance treatment program.


CLINICAL CARE PROTOCOL
Average MTS Roller application will take approximately 20-30 minutes.

Step 1) Cleaning
Thoroughly cleanse the application area.

Step 2) Apply Anesthetic
Apply local anesthetic as needed – recommended for CR5, CR10, CR20, and CR30. You may use a CR2 to deepen and quicken penetration of anesthetic. Cleanse treated area with a sponge after checking anesthesia. CRL suggests a topical anesthetic that contains benzocaine (20%), lidocaine (4%), teracaine (2%), pramoxine HCI (1%).

Step 3) Apply Solution #1
Clinical studies by Dr. B.J. Kim show that ‘double’ applications increases efficacy of the treatment modality. Apply a sufficient amount of Solution #1 per protocol directly to the treatment area.

Step 4) Treatment Roller
Divide the treatment area(s) into sub-divisions per illustration. Apply the treatment roller (CR5, CR10, CR20 and/or CR30) with the same amount of pressure on the skin throughout. Roll the same areas vertically and horizontally. Prevent lateral (sideways) movement while rolling, do not over apply pressure.

Step 5) Apply Solution #2
Apply Solution #2 liberally to the treated area. You may also apply ultrasound or Ionto to the treated areas to aid serum absorption.

Step 6) Relaxation
Apply a mask pack or other soothing application for relaxation.

Step 7) Completion
Nutrition and moisturizing management is recommended. Preventative sun-screens are also indicated.


PERSONAL CARE PROTOCOL
For greater and faster efficacy, it is recommended that the patient be prescribed a personal use MTS Roller™ (models CR2 or CR3) with topical applications such as a vitamin solution and moisturizer with sun block properties. Take a moment to instruct your patient on the proper use of their personal use roller. Personal treatment time can range from 5 to 10 minutes depending on the size of the area to be treated. The patient may repeat treatment two to three times a week. Advise the patient to stop and call you if they experience sudden and prolonged irritation in the treatment area.

Step 1) Cleansing
Clean skin, rinse thoroughly and towel dry.

Step 2) First Application
Apply first topical solution to the treatment area.

Step 3) Treatment Roller
Divide the treatment area(s) into sub-divisions, for instance the forehead, nose, cheeks, mouth area, and neck area. Apply the treatment roller with the same amount of pressure on the skin throughout. Roll the same areas vertically and horizontally.

Step 4) Second application
Massage in the second application (moisturizer or other topical).

Step 5) Finish
Allow a few minutes for the applications to be absorbed to firm and tone your skin.

Step 6) Clean Roller
Clean roller per instructions and return roller to protective case.


Cleaning the MTS Roller™

PERSONAL USE MODELS CR2, CR3: You may use denture tablets (in water) to clean the MTS Roller™. Denture tables are enzyme cleansers and enzymes take off fat as well as reduce bacteria. While not as effective, you may also use alcohol (isopropyl). Consult a pharmacist for the best advice for a sterilization solution. Open the cleaning tray and place the white cleaning pad in the larger half of the tray. Fill the cleaning tray with sterilization solution and roll the roller into the pad with medium pressure. Leave the MTS Roller in the cleaning solution for about 15 to 30 minutes – ensure that the roller drum is constantly wet with the cleaning solution. After cleaning, rinse with tap water and return the roller to the protective case and allow it to air dry. Replace the case lid until the next use.


PROFESSIONAL USE MODELS CR5, CR10, CR20, and CR30: MTS Roller™ can withstand repeated immersion in “cold sterilization” agents such as germicides (phenol, ethyl alcohol) and Cidex™ (glutaraldehyde), and common ultra-sound cleaning devices. Rinse rollers thoroughly before using and return to its protective case after drying.


Storing MTS Roller™The MTS Roller is delivered in a protective case and sealed in a sterilized pouch. Tear open the pouch at the notch and discard. After each use (and cleaning) return the MTS Roller back to the protective case. NOTE: Always treat the MTS Roller gently and avoid any contact with hard objects or surfaces. Replace all rollers that have been dropped. Keep rollers out of the reach of children.


Important Reminders
Do not use MTS Roller™ on irritated skin, infected skin, fungal skin infections, active acne, rosacea, eczema, psoriasis, severe solar keratosis, raised moles and/or warts, and/or any open wounds or sores. Patients who are not sure about their skin condition should consult a dermatologist before using the MTS Roller™.

Clinical tests have not shown any side effects from using MTS Roller™ when used as directed under the advice or supervision of a trained skin care professional. Use serums, creams and/or any other cosmeceutical or herbal topical only with the advice or supervision of a trained skin care professional.

MTS Roller™ should be stored in the supplied protective plastic box for maximum hygiene and safety after use. The instrument must be kept out of reach of children.


Using MTS Roller™ with cosmetics/cosmeceuticals.MTS Roller™ is a skin care tool that partially and temporarily pierces the topmost protective layer of skin. We advise that patients/clients apply serums, creams or other ‘topicals’ only under the direction of a qualified skin care professional. The reason is simple. Most skin care topicals (cosmetics, cosmeceuticals) are designed to be harmless while they are on the surface of the skin, however the skin may react differently when such products are infiltrated through the epidermal barrier, such as what occurs with MTS Roller™. We recommend that patients/clients speak to a qualified skin care professional if there is any doubt about the ingredients in any products and whether they are suitable for infiltration.


Sensitivity and Redness when using MTS Roller™
Patients will experience mild sensitivity and redness after treatment; signs that the fine micro points have penetrated the epidermis. The perforated stratum corneum will close within minutes and the sensitivity should abate quickly. The general redness will disappear within one or two hours of treatment. Intensity and duration of any discomfort may increase if the MTS Roller is used in combination with skin care products (cosmetics, cosmeceuticals).


GUARANTEE: 100% Contaminant-Free
MTS Rollers are sterilized with gamma radiation and sealed in a hermetic pouch and are guaranteed to be 100% contaminate-free upon delivery.

http://209.85.215.104/search?q=cache:urOL1zqJtPYJ:dermroller.com/mts-protocols.html+protocols+for+mts+roller&hl=en&ct=clnk&cd=1&gl=us

PROTOCOLS For MTS Roller™
MEDICAL and PERSONAL USE

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Tue Jun 10, 2008 10:01 pm      Reply with quote
I will start a new thread with just articles tomorrow, but this will get you started:


This is a great article on 1mm vs. 3mm rolling, and includes recommended roll frequencies from one of the inventors:

Environ® Medical Roll-CIT™ Micro-needling
Revolutionary New Approach to Medical Needling

http://www.dermaconcepts.com/2004/environ1mmNeedling1.pdf



This one focuses specifically on lip lines:

New Life for Lips
http://www.vivida.co.za/news/show_article/3



This one has a very good overview of the science behind rolling and how collagen is actually laid down within your skin:

Minimally Invasive Percutaneous Collagen Inductionhttp://www.dermogenesis.com/roll-cit/Clinics_of_N_Am_2005.pdf

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Mon Jun 16, 2008 9:42 am      Reply with quote
anya wrote:
Bethany I haven't received my 1.5mm 3Line Roller yet, but I'm sooooo happy to hear that you're loving yours Very Happy .

Don't think I'm brave enough to use that Climax Spray though Embarassed Are you washing it off before you roll?


Anya, I wiped it off with the Bactine Cleansing Spray.

And I think you will love the 3Line roller...it was really pleasure to use. Well, as much pleasure as you can have when you are poking yourself with needles! Very Happy

Image

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Mon Jun 16, 2008 2:42 pm      Reply with quote
I just wanted to follow up with the results of my 1.0mm roll last night...I actually looked pretty darn normal this morning, which was pleasant change from my first traumatic roll that kept me inside for 3-4 days.

I have done 3 rolls, with the following results:

Roll 1: I used the Super T numbing cream and the .5mm roller, and had horrific swelling (tetracaine, benzocaine and lidocaine) for 3+ days

Roll 2: I used my Rx lidocaine patches and .5mm and 1.0mm in some spots, and was just fine the next day (well, except for the severe Retin A trauma on my chest)

Roll 3: I used the Climax Spray (lidocaine) and the 1.0mm, and my skin looked pretty darn good this morning! I did have some slight bruising under my eyes where I used the 3Line roller, but nothing significant.

I also used the Bactine Spray (benzalkonium CL and lidocaine) on all 3 rolls.

My take away is that I had a significant reaction to the tetracaine or the benzocaine, though it was most likely the latter since it is known to be a significant irritant. And I now know not to use Retin-A on my chest right after a roll. But the key thing is that I continued until I could find a routine that worked for me.

So....if you are having issues with rolling, don't give up until you break things down and try to find the root cause. Otherwise you might miss out on a great anti-aging tool! Smile

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Tue Jun 17, 2008 9:02 am      Reply with quote
mogulicious wrote:
The printed material that came with the Dermarollers.us models indicates that 1.0 can be used once weekly, and 2.0 once every three weeks.

MB935 wrote: I have the 2.0 from this company and I dont remember reading that... does it then say when to take a break??? Cause Ive already rolled twice in 2 weeks...

I guess most of us are confused on how often to use these things... Its almost annoying because none of us want this tool to be a waste of time in the end (delaying or even ruining hte collagen production process)...

MB935, I located the papers from dermarollers.us. Here's a brief summary:

The chart lists minimum time between treatments and recommended time between treatments:

.25 1 day minimum; 2-3 days recommended
.5mm 3 days minimum, 5-7 days recommended
1.0 1 week minimum, 2-4 weeks recommended
1.5 2 weeks minumum, 4-6 weeks recommended
2.0 3 weeks min, 4-6 weeks rec
2.5 4 weeks min, 4-6 weeks rec
The number of treatments will depend on the skin condition. Three to four treatments are recommended. Depending on the results, treatment may be repeated to achieve maximum results. The formation of new collagen requires time to mature, it is therefore recommended to do each CIT treatment 4-6 weeks apart. And an annual upkeep treatment should also be considered. The home care dermaroller (.25 & .50) in combination with skin care products can be used in between treatments with the medical dermaroller (1.0 +), this will enhance the results of CIT treatments. It is also recommended to take vitamin C supplements since vit c is essential to the collagen production.

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Wed Jun 18, 2008 2:47 pm      Reply with quote
Dermarollers.us emailed the following:

THANK YOU FOR YOUR DERMAROLLER PURCHASE

If you are not already familiar with the dermaroller product, please take a few minutes to read the accompanying literature and learn more.

The dermaroller is a simple, yet innovative hand tool that can help with many skin problems such as acne scars, hyper pigmentation, aged skin, stretch marks, and more.

Summary About the dermaroller

Skin needling with the dermaroller can be performed on the skin of any part of the body including the scalp. The roller is inlayed with 192 very fine stainless steel needles, available in different lengths..

Mechanism of action

By rolling the dermaroller on the skin, micro punctures and channels are created. This serves two purposes. First, it induces collagen/elastin production naturally by the skin through the release of growth factors. Second, by applying a topical cream/lotion/serum on the skin and rolling the dermaroller over it, absorption and penetration of active ingredients is enhanced hundreds of times (normal skin absorption of topical application is as low as 0.3%) as they seep deep into the skin through the micro channels exerting their beneficial effects.

Indications

Effective in:

. Smoothening fine lines and wrinkles.

. Pores size reduction.

. Improving scars caused by acne/chicken pox/trauma.

. Improving the appearance of stretch marks/striae/cellulite.

. Improving skin texture as a result of firmer and more lifted skin.

. Reducing skin pigmentation and enhancing whitening of skin through appropriate active ingredient delivery.

. Treating alopecia (hair loss) for both men and women.

Contra-Indications

Do not use on irritated skin, infected skin, active acne, rosacea, eczema, psoriasis, raised moles, warts, open wounds or sores. If unsure, consult a doctor before use.

The dermaroller is for exclusive personal use only. Do not share it with anyone else.

Do not apply ingredients that you are sensitive to on the face.

Keep it out of the reach of children and animals.

Precautions:

Avoid eyes area. If persistent redness or irritation occurs, discontinue use and consult a doctor or skin care professional.

Directions for use (These are general recommended directions. If you doctor/skin care professional has provided you with specific directions, follow those instead)

Home care (needle length 0.5mm and below)

- Clean skin before use. Divide the treatment areas into sub-divisions, e.g. the forehead, cheeks, nose, chin, neck etc, treating each sub-division one at a time.

- Mix a sufficient amount of topical products and apply on the sub-division to be treated.

- Roll the dermaroller on the sub-division as shown, 4 - 10 times in each direction, horizontally, vertically and diagonally.

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- Apply topical products onto the skin again after treatment.

Medical use (needle length 1.0mm and above)

- Clean skin before use. Divide the treatment areas into sub-divisions, e.g. the forehead, cheeks, nose, chin, neck etc, treating each sub-division one at a time.

- Apply numbing cream/gel and wait the indicated time for the anesthetic to take effect. Remove any excess cream/gel before proceeding to rolling.

- Roll the dermaroller on the sub-division as shown, 4 - 10 times in each direction, horizontally, vertically and diagonally.

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It is recommended to take vitamin C supplements while doing collagen induction therapy (CIT) treatments. Vitamin C is essential in the production of collagen.

Do not use excessive force when rolling the dermaroller onto the skin. Use only mild pressure.

Start using the home care dermaroller once or twice per week. Once your skin gets more used to it, you may increase treatment frequency.

The longer the needle length, the more you should wait in between treatments. See table below for recommended time you should wait between treatments, if unsure, consult a doctor before use.

Needle Length
Minimum time between treatments
Recommended time between treatments

Home Care
0.25mm
1 day
2 – 3 days

0.5mm
3 days
5 – 7 days

Medical Care
1.0mm
1 week
2 – 4 weeks

1.5mm
2 weeks
4 – 6 weeks

2.0mm
3 weeks
4 – 6 weeks

2.5mm
4 weeks
4 – 6 weeks

Post Treatment

. Mask, moisturizer and sun-screens may be applied after treatment.

. Mild erythema, warmth, swelling and sensitivity of the skin may be experienced post treatment. Consult a doctor if in doubt.

Maintenance of dermaroller

- Rinse the dermaroller with tepid water after use.

- Soak the head of roller in an anti-septic solution such as alcohol for about 5 minutes. Let dry completely before storing in the protective casing provided.

Do not store dermaroller in casing until completely dry.

Do not expose it to very high temperatures.


Specifications

Roller Body: Diameter 20mm
192 medical grade stainless steel needles
Advanced superior sterilization by EO Gas, non-toxic, pyrogen free

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The different dermaroller models available

Dermarollers are available in several needle lengths.

Those that have a needle length of 0.5mm and below are usually classified as home care, while those with a needle length of 1.0mm and above are classified as medical care.


PERSONAL HOME USE – can be used at home whenever you wish

0.25mm dermaroller

Used to enhance effective delivery of skin care products into the skin
The treatment is virtually pain free
Apply your cosmetic on the skin and roll it in
The process stimulates physiological responses
It can be used by yourself at home or anywhere
There is no damage to the skin
It can be used on thin skin
Improves overall skin texture and color
CLINIC USE – experience an increase in hair growth

0.5mm dermaroller

Promote new hair growth in 3 months

Men treated with the 0.5mm dermaroller experienced an increase in hair growth and an average 80% reduction in hair loss.
Improved cell-growth
Optimized effects
Minimal dosage
Perfect flow-characteristics
One daily treatment only
Best value for the best price
MEDICAL USE – skin remodeling

1.0mm, 1.5mm, 2.0mm and 2.5mm dermarollers

There is a very short healing period.
It can safely be repeated for better results.
It can be used on laser resurfaced skin.
The first advantage is that this procedure does not permanently damage the skin.
The skin actually becomes thicker.
Low cost alternative to more expensive procedures.
Sun-sensitivity is a major and enduring problem in laser resurfacing, whereas after needling of the skin, the horny layer rapidly returns to its original thickness and the skin is not as sensitive to the sun..
If the result after the percutaneous collagen induction is not satisfactory to the patient, it can be repeated without any risk.


What needle length should I use?

Your doctor/skin care professional should indicate which needle roller is the most appropriate for the condition you wish to treat. Below are some examples.

Needle length
Uses

0.25mm
Increased penetration of skin care products into the skin and overall improvement of skin color and texture, thinning hair

0.5mm
Increased penetration, less invasive CIT. Alopecia, wrinkles, mild pigmentation, general skin rejuvenation

1.0mm, 1.5mm
Standard CIT. Acne/chicken pox scars, stretch marks, wrinkles, elasticity decline, cellulite, pigmentation

2.0mm, 2.5mm
More aggressive CIT for more severe cases, deep scars and wrinkles, rejuvenation of ruined skin


HOME CARE DEMAROLLER – 0.5mm and below

Use of the home care dermaroller increases effective delivery of active ingredients in skin care products by hundreds of times. It improves overall skin texture and color. It helps you achieve faster results with your existing skin care products by dramatically increasing their effectiveness.

MEDICAL USE DERMAROLLER – 1.0mm and above

Collagen Induction Therapy (CIT)

As the name implies it, collagen induction therapy (CIT) is a procedure that stimulates the production of new collagen in the skin.

Various ablative procedures, such as dermabrasion, acid peeling, and laser resurfacing have been used for skin rejuvenation. These ablative procedures have many disadvantages and risks. For one, the protective epidermis is removed. Once the epidermis is removed, the skin is fully exposed to elements in the environment such as dirt, bacteria, etc.

These procedures are expensive and have many disadvantages. The epidermis is removed, skin becomes thinner, long healing time, high sun sensitivity, high risks and side effects, possible hyperpigmentation and/or depigmentation, possible new scars, and further treatments may not be possible due to the skin becoming too thin..

CIT changes all that. CIT works differently, the treatment is very simple. When the dermaroller is rolled over the skin, the very fine needles create hundreds of deep microscopic channels, which stimulate the body’s own functions to produce collagen.

When the skin is micro needled, a reaction occurs, chemical compositions, protein and growth factors are released by skin cells. A migration of proliferated cells occurs to the injury where they transform into collagen fibers.

The advantages of CIT with the dermaroller over traditional ablative procedures are obvious: the epidermis stays intact, the skin actually becomes thicker, healing time is very short, no post treatment pain, little or no sun sensitivity, no reported risks or side effects, treatment can be repeated as often as necessary and the cost is very low compared to other procedures.

Unlike ablative procedures, CIT can be performed on all skin areas and may be repeated many times.

During a CIT treatment, the epidermis will stay intact and the microscopic channels created during the procedure will close within minutes. After a CIT treatment, the face will be red, this will fade in a day or two.

The number of CIT treatments will depend on the skin condition. Three to four treatments are recommended. Depending on the results, treatment may be repeated to achieve maximum results.

The formation of new collagen requires time to mature, it is therefore recommended to do each CIT treatment 4-6 apart. And an annual upkeep treatment should also be considered.

It is also recommended to take vitamin C supplements since vitamin C is essential to the collagen production.

The home care dermaroller in combination with skin care products can be in used in between treatments with the medical dermaroller, this will enhance the results of CIT treatments.

Stretch Marks / Striae

Stretch marks or striae are caused by skin stretching during rapid growth. This occurs most often during puberty and pregnancy. When the skin over stretches, it ruptures and these ruptures become scars. At first, stretch marks appear red to purple in color, as time goes by, they usually become white. Unfortunately, stretch marks are permanent and are not easy to treat. Traditional treatments with lasers or creams usually yield little results. Stretch marks do not affect any function of the body; however, they can be unsightly and this can lead to emotional distress.

CIT offers new hope in the treatment of stretch marks. The results from micro needling with a dermaroller to treat stretch marks have been very positive and beyond expectations.


Acne Scars

Acne is a common skin condition. It affects more than 85% of teenagers and often continues into adulthood.

In many cases, acne can also leave permanent scars. Acne scars can have a very psychological impact on the person suffering from this condition.

Acne scars are difficult and expensive to treat.

CIT with the dermaroller has been used effectively to treat and reduce the appearance of acne scars. This is an easy, very cost effective procedure with no down time.

Important Note: Acne must be completely healed before performing acne scar treatment with the dermaroller,


Hyper Pigmentation

Hyperpigmentation is caused by increased melanin concentration on an area of the skin, which makes it appear darker than the surrounding area. Though hyperpigmentation usually fades away with time, in some cases this can be permanent.

The results from treating hyper pigmentation with CIT have been very good. After a couple of treatments the skin usually returns to its normal pigmentation.

Sunscreen should be used after the CIT procedure and sun exposure should be avoided in general.

Wrinkles

Wrinkles typically appear as a result of the aging process. As we age, our skin becomes thinner and loses elasticity. The degradation of collagen that comes with aging leads to wrinkles.


CIT by means of micro needling can help stop this by promoting cell regeneration.

The number of treatments required will depend on the individual’s skin condition. Initially one to three CIT treatments is advised. And an annual upkeep treatment should be considered.

As always, it is best to avoid direct sun exposure. Sunscreen should always be used when doing outdoors activities.

Hair Loss

The derma roller can be used by itself or in combination with products such as Minoxidil, Rogaine or similar products. Used by itself it can stimulate collagen production and fine hairs. When used in combination with hair loss products, their effectiveness is increased due to enhanced penetration of active ingredients into the scalp produced by using the dermaroller.

The way the dermaroller is rolled on the scalp is a little different than when used on other parts of the body.

- Wash scalp and dry very well.

- Roll the derma roller gently over the same area only in one direction 2-3 times. (Rolling back and forth will cause existing hair to tangle in the roller). Roll away from the hair root. Use your hands to keep existing hair out of the way as much as possible.

- Apply hair loss product and massage.

Repeat treatment once a day or as directed by a professional.



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Mon Sep 16, 2019 6:17 pm
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