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does idebenone NOT work at all for some people! (irritation)
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youngrace
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Fri Dec 21, 2007 3:52 am      Reply with quote
i think my skin hates idebenone. i've tried probably five different formulations, and all seem to irritate the heck out of my face. so i'm curious--is this irritation similar to the type you get with vitamin c, and that goes away after a while, or is this something that will keep on going long after i've used up my tubes of ea prevage and prevage md? if so, i probably won't be doing my skin a huge service anyway. Laughing thanks everyone in advance!
AnnieR
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Fri Dec 21, 2007 7:52 am      Reply with quote
I cannot use any Prevage at all, little tiny bumps. but they disappear after a couple weeks of nonusage.

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Niniya
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Fri Dec 21, 2007 9:03 am      Reply with quote
seems a little bit horrible, I'm thinking about buying myself idebenone products, but now may should be more cautious><
youngrace
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Fri Dec 21, 2007 11:51 am      Reply with quote
sorry--i should have been more specific. =) i meant the irritation that goes away after you use the product for a bit; you know how dermatologists are always like, "stick with it--the irritation goes away but the results last forever." that sort of thing. anyone know?
bugaboo
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Fri Dec 21, 2007 12:10 pm      Reply with quote
Some people can have allergies to this. I have made a DIY lotion from the products at skinactives.com where they sell Idebenone in the raw form. They mention in the product description that there can be an alergic reaction. I don't have any though, it does wonders for my skin!
BluesHeart
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Fri Dec 21, 2007 12:29 pm      Reply with quote
I've been using a product that contains this ingredient and my skin loves it. It does seem to one that you either can or can't.

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lipglossdoll
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Fri Dec 21, 2007 12:56 pm      Reply with quote
I had an AWFUL reaction to prevage. Scaly, reddened patches of skin. I use many products, (too many, lol!) , but this one really wrecked havoc on my skin at the time.
lipglossdoll
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Fri Dec 21, 2007 12:59 pm      Reply with quote
Oops, forgot to add that yes, it does sound like an allergic reaction, many people are sensitive to idebenone.
If I were you , I would not keep using it, hths. Smile
red head
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Fri Dec 21, 2007 1:00 pm      Reply with quote
It made my face itch and burn also can't use the makeup that has it in it
Mariav
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Fri Dec 21, 2007 1:51 pm      Reply with quote
No go for me either...I broke out in a rash all over my face and neck...I didn't even think I got any of the Prevage on my neckt! It was pretty bad and took several days to go away.

Little tiny bumps are also a side effect for me for Vitamin C - can't use that either....

Maria Laughing

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youngrace
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Fri Dec 21, 2007 4:11 pm      Reply with quote
thanks everyone for the feedback! i guess that settles it for me...no idebenone for sensitive skin. Confused i guess it's back to the drawing board...
nickieygirl
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Sat Dec 22, 2007 3:09 am      Reply with quote
I could happen to anyone. Stop to use it if any irritation occurs.
fawnie
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Sat Dec 22, 2007 5:21 pm      Reply with quote
My derm rec going very slowly at first with Prevage (idebenone) d/t irritation. She rec every other day after a patch test first to rule out allergy. She said some ppl will break out in a rash or acne. Since Prevage MD is 1% and OTC Prevage is 0.5% be very careful with the MD strength.
The info about it is very confusing, also. Skinactives.com rec not using it with acids, but my derm rec using it over my glycolic products.
I personally have not had any probs with it and use the MD strength day and nite. Goes to show how different we are! Bummer that it happened to you tho Youngrace. =(

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cbw
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Mon Dec 24, 2007 3:59 am      Reply with quote
I am in day four of a terrible allergic reaction to Idebenone 1%. My face is swollen, itchy and burning. I have tried everything I can think of to help, but nothing seems to work. I have used many, many, many products for my skin and nothing has ever given me a bad reaction until this. It is horrible!!!!!!!
AnnieR
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Mon Dec 24, 2007 8:27 am      Reply with quote
My derm said that taking Benedryl can sometimes help or they prescribe prednisone or a methpack (methylprednisone?) for more severe cases. I use Obagi Active lotion for several days to speed healing. I would suggest calling your doc if at all possible right now and it is not improving. That's a pretty strong reaction. Hope it gets better soon.

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SusieQ
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Mon Dec 24, 2007 10:06 am      Reply with quote
I have heard of this Idebenone. Not good. There are no clinical studies to prove its good for skin. There are some products that do stimulate formation of collagen and thats retin A or Differin.....maybe vitamin C (but its not stable) so forget that. AHAs and glycolics are wonderful for skin as well. That cancels everything else OUT. Take your pick. You will see results with very little irritation if you use any ONE of these products on your skin with NOTHING ELSE sparingly. Good luck!
Mau
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Tue Dec 25, 2007 8:02 am      Reply with quote
This spring I used Perfect Complexion's HA Soy Lift. I experienced mild irritation after each application and each time I thought it's OK ("stick with it--the irritation goes away but the results last forever"). I used half of the bottle when I saw a suspicious red spot with tiny bumps under my right eye (on the cheek). It looked so unusual that I checked all google images typing "skin cancer". Moreover, I visited a doctor soon and he said that it was a siringioma (?) (benign skin tumor). I visited two more doctors after that and all of them pronounced different diagnosis including "just" dermatitis.
But I think that it was a reaction on this product only. Mad
I stopped to use everything that time including Copper peptides serum. I exfoliated my skin with acids occasionally. The spot almost disappeared after couple of months. It is hardly visible now but still there. You can see it if you know where to look Sad
Be very careful and don't ignore if your skin reacts. ANY way. Exclamation

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majorb
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Wed Dec 26, 2007 8:56 am      Reply with quote
cbw wrote:
I am in day four of a terrible allergic reaction to Idebenone 1%. My face is swollen, itchy and burning. I have tried everything I can think of to help, but nothing seems to work. I have used many, many, many products for my skin and nothing has ever given me a bad reaction until this. It is horrible!!!!!!!


I experienced this too, around my eyes. The itching was unbelievable.

Have you any hydrocortisone cream? I'd apply that (sparingly) and nothing else until the itching and other symptoms subside. Be careful not to apply it for longer than 7 days, though, as it can thin the skin.

After that, I found my skin to be extremely dry, crinkled and still red. So I applied a nice, mild face cream without active ingredients and followed with a layer of vaseline. Several days later, my skin was looking and feeling so much better.

If your skin doesn't appear to be healing well, though, you might be best to check with your doctor.
cbw
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Wed Dec 26, 2007 7:20 pm      Reply with quote
Thanks for everyone's advice. Day 6 and my skin is starting to heal. My face and neck are very dry and starting to peel - Kind of like that chapped skin that comes from snow skiing.
I have peels and treatments regularly, but I hope to never use this stuff again!!!!
cbw
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Wed Dec 26, 2007 7:20 pm      Reply with quote
Thanks for everyone's advice. Day 6 and my skin is starting to heal. My face and neck are very dry and starting to peel - Kind of like that chapped skin that comes from snow skiing.
I have peels and treatments regularly, but I hope to never use this stuff again!!!!
majorb
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Fri Dec 28, 2007 2:50 am      Reply with quote
I'm glad your skin's starting to recover. Now you should be sure to take good, gentle care of it until it's fully mended. I'd definitely recommend vaseline over a nice, gentle face cream.
maiea
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Sat Dec 29, 2007 2:08 am      Reply with quote
Yeah, people can get allergic reactions to idebenone since it is a synthetic molecule.. unfortunately I don't think there's much you can do about it if you have an allergy to the product, if you persist, the allergic reaction might just get worse.
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