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What Products are on your No-No List?

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Joined: 18 Jan 2012
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Wed Jan 18, 2012 3:54 pm      Reply with quote
My no-no list Smile

3.Mary Kay-uggh!
7.Philosophy's Miracle Worker set-guess what? No Miracles.
8.Dermalogica-my friend tried many products on me and I had plenty of samples and kits I purchased from her-this by far did the most damage.
9. and finally REN.-my skin was terrible after two weeks-TERRIBLE!
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Thu Mar 01, 2012 7:01 pm      Reply with quote
Maybelline great lash mascara. It always pops up in beauty magazines. I always comeback to it after a few years thinking I must be wrong. it's garbage. The brush and formula are both so old fashioned. there are so many better mascaras out there now.

Neturogena Acne face washes. I got a terrible rash that took weeks to get rid of.
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Sat Mar 03, 2012 10:17 am      Reply with quote
jom wrote:
DrJ wrote:
My "bad boy" list:

Anything with EGF (epidermal growth factor) as the only cytokine ... there is a reason they use this to take the wool off sheep.

Anything with Teprenone(so called DNA cream)... anti-ulcer drug that induces heat shock proteins. You want your face covefred in mucous like the lining of your stomach?

I have more. Great thread.

What other ingredients are cytokines?

Hi jom,

Cytokines are the natural chemical molecular signals that human skin cells use to talk with one another. They are also called "signal transduction molecules" which means the same thing. They include many different families. Some are involved with stimulation to divide and make new cells and are called growth factors. Others are involved with inflammation, mopping up damage. There are hundreds of different ones. Cell-to-cell communications are at the very core of responding to damage (e.g. from UV rays), which has to be a coordinated process, not just one cell type. It involves stem cells, fibroblasts, and epithelial cells. These same cytokines are also altering the expression of many cell proteins, including enzymes, etc. The whole regenerative process is mediated by these chemicals. They are also, therefore, intimately tied up with aging (and therefore also with strategies for anti-aging, especially skin).

Now, EGF is a growth factor, and thus a cytokine. If you apply it to skin it will cause proliferation (growth, "plumping" & thickening of skin. But when you give it alone, it is not physiologic, which means it doesn't work like nature intended. Instead it is pharmacologic in action, and can have untoward effects. Whereas if you give it in a cocktail of cytokines (see thread here on ISCO product, which is a bit more physiologic), there are checks and balances.

Pure EGF is used in the sheep industry as a way to take wool off - easier than shearing. How does that work? You give enough, the skin puffs up and pores are choked off, which causes the hair to fall out.

We have several articles on cytokines, as well as on EGF at barefacedtruth. (somebody else will have to provide the link)
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Sat Mar 03, 2012 10:21 am      Reply with quote
Oh, and all the products that say they contain "conditioned media" (e.g. from fibroblasts, like Skinmedica's TNS, or from stem cells) ... well the active ingredients really are a host of cytokines. There are some other things in there (some sugar, some proteins) but these are just by products, and not the active or working ingredients.
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Sun May 27, 2012 3:45 pm      Reply with quote
La Mer is on my no no list due to the cost. I just don't think the ingredients offer enough to justify the expense.
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