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Mixing No-Nos
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jhillo
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Sat Oct 15, 2011 6:56 pm      Reply with quote
We all know never to mix (or layer) Vitamin C and Copper Peptides.
What are some other mixing no-no's?

Is it ok to mix Retin-A with Vitamin C?
Is it ok to mix Retin-A with AHA?
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Sun Oct 16, 2011 12:12 am      Reply with quote
I wouldn't mix retin-a with AHAs, or any other acid for that matter, you'll end up with a mess of inflamed skin.

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Sun Oct 16, 2011 12:14 am      Reply with quote
AHA's inactivate Retin-A Wink
UmEnis
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Sun Oct 16, 2011 4:29 am      Reply with quote
How do Retin-A and the AHA's neutralize each other?
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Sun Oct 16, 2011 6:30 am      Reply with quote
I'm not sure what the process is but my skin specialist (and she has 32 years experience and has a Health Science degree) has told me that glycolic acid/AHA's inactivate Retin-A - probably a bit like Benzoyl Peroxide inactivating Retin-A.

Before I knew about this reaction I had previously used glycolic and Retin-A together and it left my skin an inflammed irritated mess - that's just my experience, so I'm not sure if it is this irritation that is the result of the inactivation of the Retin-a.

I'm sure there is someone who has a scientific answer for it on EDS Wink
echoecho
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Sun Oct 16, 2011 7:41 am      Reply with quote
Glamcat wrote:
I'm not sure what the process is but my skin specialist (and she has 32 years experience and has a Health Science degree) has told me that glycolic acid/AHA's inactivate Retin-A - probably a bit like Benzoyl Peroxide inactivating Retin-A.

Before I knew about this reaction I had previously used glycolic and Retin-A together and it left my skin an inflammed irritated mess - that's just my experience, so I'm not sure if it is this irritation that is the result of the inactivation of the Retin-a.

I'm sure there is someone who has a scientific answer for it on EDS Wink


I am using Glycolic and Retin-A together woops, thank you for the info. If I still wanted to use both actives though what would be a good method of doing it?

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AGE: 25. Some laxity, fine lines, rosacea, and crepey skin. USING: Tripollar STOP, Lightstim, Slendertone Face, Microcurrent Wand, Almighty Ultrasound Device, Olay Cleansing Brush, Neck Line Slimmer. Retin-A, MUAC peels, and taking beauty supplements. Botox eyebrow lift and HG lip products are Too Faced.
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Sun Oct 16, 2011 7:55 am      Reply with quote
Glamcat wrote:
I'm not sure what the process is but my skin specialist (and she has 32 years experience and has a Health Science degree) has told me that glycolic acid/AHA's inactivate Retin-A - probably a bit like Benzoyl Peroxide inactivating Retin-A.

Before I knew about this reaction I had previously used glycolic and Retin-A together and it left my skin an inflammed irritated mess - that's just my experience, so I'm not sure if it is this irritation that is the result of the inactivation of the Retin-a.

I'm sure there is someone who has a scientific answer for it on EDS Wink


She might have meant the other ingredients in a Glycolic/AHA product can inactivate RA.

Glycolic acid can actually enhance penetration (and cause increased irritation).

http://www.ncbi.nlm.nih.gov/pubmed/15724102
echoecho
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Sun Oct 16, 2011 8:06 am      Reply with quote
Well I'm going to postpone changing until theres more information on the subject then Razz

How does the glycolic help the Rentin-A penetrate better?

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AGE: 25. Some laxity, fine lines, rosacea, and crepey skin. USING: Tripollar STOP, Lightstim, Slendertone Face, Microcurrent Wand, Almighty Ultrasound Device, Olay Cleansing Brush, Neck Line Slimmer. Retin-A, MUAC peels, and taking beauty supplements. Botox eyebrow lift and HG lip products are Too Faced.
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Sun Oct 16, 2011 8:14 am      Reply with quote
echoecho wrote:


How does the glycolic help the Rentin-A penetrate better?


Per the article that circus linked to:

"CONCLUSION:

These observations indicate that the addition of an AHA such as GA to a retinoid such as RAL results in a better bioavailability of the retinoid, thus a higher delivery of RA, which potentiates the biological activities of the retinoid. This combination allows a delivery of high amounts of RA in the skin while preventing the side-effects usually observed with high concentrations of topical RA."
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Sun Oct 16, 2011 8:18 am      Reply with quote
Thanks for that, I have to admit not looking at that just reading the rest of the quote, I guess a good Retinol product should also include the Glycolic for a stronger formula. Smile

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AGE: 25. Some laxity, fine lines, rosacea, and crepey skin. USING: Tripollar STOP, Lightstim, Slendertone Face, Microcurrent Wand, Almighty Ultrasound Device, Olay Cleansing Brush, Neck Line Slimmer. Retin-A, MUAC peels, and taking beauty supplements. Botox eyebrow lift and HG lip products are Too Faced.
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Thu Oct 20, 2011 11:49 am      Reply with quote
echoecho wrote:
Thanks for that, I have to admit not looking at that just reading the rest of the quote, I guess a good Retinol product should also include the Glycolic for a stronger formula. Smile


The Avene Triacneal is based on Retinaldehyde and Glycolic if you'd like to try. This is the improved version replacing Diacneal.
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Fri Oct 21, 2011 9:58 am      Reply with quote
I do not mix Retin A with anything, I use it at night and only use Emu oil after application to hydrate and minimize irritation, but I use Vic C in the morning then. the upper layer (dead skin) rolls off easier and the new layer is healthy then.
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