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Tue Apr 24, 2012 1:55 pm |
DrJ wrote: |
Debb3485 wrote: |
Debb3485 wrote: |
DrJ wrote: |
The superstar active in AnteAGE is a collection of chemicals called cytokines whose pattern is specifically tuned to deal with skin rejuvenation. There are multiple mechanisms involved. It is not limited to a single construct like "DNA repair". DNA repair only does one thing - tries to rescue cells that have potential to mutate or die due to DNA damage.
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DrJ, I am new to this forum but have been reading the posts about AnteAge and have ordered a sample. Yesterday I received a flyer in the mail for a product called Duplicell P199 which claims it is "The Most Advanced Formula Ever Released in the History of Skin Care". It says it diminishes the appearance of wrinkles by 56%, Increases collagen production by 84%, Decreases looseness of skin by 54% and in 5 days increases exfoliation by 84.7%. It claims to stimulate epidermal growth factors to start reproducing your own dormant stem cells and also uses protein peptides developed by Dr. Boris Petrikovsky, MD, PhD. I could not find a website address on the literature, just a phone number. This product only costs $49.95 (w/o shipping) for a one month supply whereas your product includes two items at a price of $280. Do you know anything about Duplicell P199 and if so, can you explain the differences between AnteAge and Duplicell P199 and why your product is a better choice? |
DrJ, One more question, P199 is also the peptide in Kate Somerville's CytoCell so I also question why Duplicell is so revolutionary since Cytocell has been on the market for a while now. Thanks for your comments. |
Hi Debb3485. Glad to have you with us.
Some cosmetic companies seem almost cynical in their approach to consumers. You are all so easy to fool, they think. Marketing generally triumphs over science in these enterprises.
Kate Somerville is one of those. Throw in a few moisturizers, then add a very small quantity of an active that everyone else has, but call it something else to make it sound special. Then charge far more than the ingredients are worth.
As Exhibit #1 consider Deep Tissue Repair
Cream with Peptide K-8. The bold claim on the web site says "Peptide K8™, a Kate Somerville exclusive, is designed to dramatically improve skin’s texture and tone.
Then read the actual ingredients, which by law have to be real. Way down near the bottom of the list is Palmitoyl Oligopeptide. That's a real peptide, the original Matrixyl (not 3000), and not expensive.
On to P-199, and the CytoCell product. Claim: "Peptide P-199 refreshes the skin’s healthy appearance." But on the label the only peptide is Polypeptide-72 which exists nowhere. It's not in any scientific literature. Not in the ingredients manufacturers listings. Further as a polypeptide with (by inference) 72 chains it is unlikely to be absorbed unless liposomized, of which there is no mention.
Actives in "marketing" quantities, or total figments of a fertile imagination. Either way, they score high on my list of companies that get under my skin, not on my skin.
Boris Petrikovsky MD PhD is an OB/GYN in new York. If you google him along with P-199 all that show up in the search list is scam sites, and russian web sites. The kind you want to make sure your antivirus filters are on when you visit.
Appaently he "advises" a company he also owns (ABG labs) in NY, and has come up with something he calls a "wharton's jelly" peptide that he uses in mesotherapy (injections) and calls meso-wharton P-199. If you then Google meso-wharton P-199 you will get a search results list full of mostly Russian web sites (Cyrillic).
This reminds me a lot of the Amatokin story... Secret peptide THAT STIMULATES YOUR OWN STEM CELLS (bunk) from hidden labaoratory in former USSR surrounded by barbed wire fence (a prison maybe full of bunco artists?).
Here is one translated into English. You can tell its a translation because the sentences are not in usual English word order. Like
Meso-Wharton P199™ intended for intense repair and rejuvenation of the face after 35-40 years by direct action on the proliferative properties of tissue-specific stem cells localized in the skin. Can you hear the Russian accent when you read this? Very awkward wording.
There is even research on the site. Problem is, the results don;t quite add up to what they say they do. I'll summarize briefly. They add their magic ingredient to some human cell cultures and then measure cytokines. These are interleukin cytokines and a few growth factors. I have written elsewhere about how you can take many things and add them to cell cultures and see increased mitogenesis (stimulation of cell division). Including a lot of toxins. The interleukins are the clue that this is a stress response, not a healing response. There are a few other equally unhelpful experiments. I would conclude that Dr. P is a neonatologist, not a cell biologist.
I'll let others comment on the differences between all this and the AnteAGE story. |
DrJ, Thank you for your detailed analysis. I can certainly tell that you did a little research. You are correct as the literature I received says that Dr. Petrikovsky specializes in Fetal Physiology and performs in-utero surgery and that he surmised that something in Wharton Jelly caused the babies surgical sites to completely heal which lead to his discovery which isolated the peptide. The literature then says he was able to create a synthetic peptide that copies the chemical makeup of Wharton Jelly and that this peptide is named P199. So I would surmise that he developed P199 which Kate Somerville says is in Cytocell. I am certainly one who falls for marketing schemes and so I tend to be a serial skin care product purchaser. I am looking forward to getting the samples of the product you developed. The price doesn't bother me as I've bought La Mer, La Prairie, Sisley, Perricone, PTR, etc so if I see good results I will purchase and hopefully stay with the product for some time. But looking forward to more posts from you about your products as well as your analysis of other products in the market. |
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Tue Apr 24, 2012 2:14 pm |
rileygirl wrote: |
DrJ wrote: |
OK, so you want a pure cytokines DIY product.
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Hmm, so it sounds like you will make this available to "select" suppliers? If you do this, what then will make your product standout and be "special" amongst all the other stuff out there? |
Philosophy not strategy, so no promises here. This is our baby. When your baby grows and develops you want them to have a life outside the family of origin. We don't want to be stifling our offspring. Also - we are dedicated to being on the leading edge. We already have new science in the pipeline. So we think we will always have some advantage.
Also, the beauty of chemistry is that ingredients can always be combined in new and exciting ways. Great chefs, great cookbooks, creative cookery. I think the DIY community is like a collection of innovative off the beaten path family restaurants experimenting with cuisine, and I want to be the Tony Bourdin of cosmeceuticals. |
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Tue Apr 24, 2012 2:19 pm |
Debb3485 wrote: |
DrJ, Thank you for your detailed analysis. I can certainly tell that you did a little research. You are correct as the literature I received says that Dr. Petrikovsky specializes in Fetal Physiology and performs in-utero surgery and that he surmised that something in Wharton Jelly caused the babies surgical sites to completely heal which lead to his discovery which isolated the peptide. The literature then says he was able to create a synthetic peptide that copies the chemical makeup of Wharton Jelly and that this peptide is named P199. So I would surmise that he developed P199 which Kate Somerville says is in Cytocell. I am certainly one who falls for marketing schemes and so I tend to be a serial skin care product purchaser. I am looking forward to getting the samples of the product you developed. The price doesn't bother me as I've bought La Mer, La Prairie, Sisley, Perricone, PTR, etc so if I see good results I will purchase and hopefully stay with the product for some time. But looking forward to more posts from you about your products as well as your analysis of other products in the market. |
Thanks Debb3485. Could you share the address or phone # on that brochure? Maybe we could take an even closer look, and call the company. Maybe there is new information. Always want to keep an open mind. |
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Tue Apr 24, 2012 2:38 pm |
DrJ wrote: |
Philosophy not strategy, so no promises here. This is our baby. When your baby grows and develops you want them to have a life outside the family of origin. We don't want to be stifling our offspring. Also - we are dedicated to being on the leading edge. We already have new science in the pipeline. So we think we will always have some advantage.
Also, the beauty of chemistry is that ingredients can always be combined in new and exciting ways. Great chefs, great cookbooks, creative cookery. I think the DIY community is like a collection of innovative off the beaten path family restaurants experimenting with cuisine, and I want to be the Tony Bourdin of cosmeceuticals. |
Thanks, Dr. J! The bolded above is very intriguing! |
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Tue Apr 24, 2012 2:58 pm |
Dr J - Just wondering if there's any chance that those of us from the UK who have a US shipping address but a UK billing address will be able to order from your site soon? At the moment, the billing addresses are set up only for the US, Australia and Canada. |
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Tue Apr 24, 2012 3:50 pm |
DrJ wrote: |
Debb3485 wrote: |
DrJ, Thank you for your detailed analysis. I can certainly tell that you did a little research. You are correct as the literature I received says that Dr. Petrikovsky specializes in Fetal Physiology and performs in-utero surgery and that he surmised that something in Wharton Jelly caused the babies surgical sites to completely heal which lead to his discovery which isolated the peptide. The literature then says he was able to create a synthetic peptide that copies the chemical makeup of Wharton Jelly and that this peptide is named P199. So I would surmise that he developed P199 which Kate Somerville says is in Cytocell. I am certainly one who falls for marketing schemes and so I tend to be a serial skin care product purchaser. I am looking forward to getting the samples of the product you developed. The price doesn't bother me as I've bought La Mer, La Prairie, Sisley, Perricone, PTR, etc so if I see good results I will purchase and hopefully stay with the product for some time. But looking forward to more posts from you about your products as well as your analysis of other products in the market. |
Thanks Debb3485. Could you share the address or phone # on that brochure? Maybe we could take an even closer look, and call the company. Maybe there is new information. Always want to keep an open mind. |
DrJ, the phone number is 1-800-941-5905, customer service # is 888-232-1834 and there is a mailing address of 56 West 45th St, Suite 1001 New York, NY 10036. I'd be curious what else you find out about the product. Thank you! |
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Tue Apr 24, 2012 4:32 pm |
majorb wrote: |
Dr J - Just wondering if there's any chance that those of us from the UK who have a US shipping address but a UK billing address will be able to order from your site soon? At the moment, the billing addresses are set up only for the US, Australia and Canada. |
Let me look into that. Sounds like an easy fix. |
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Tue Apr 24, 2012 4:34 pm |
jom wrote: |
DragoN wrote: |
For Jom.
Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier.
Tanno O, Ota Y, Kitamura N, Katsube T, Inoue S.
Source
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Thanks DragoN
Just for clarification purposes, Nicotinamide is the same as niacinamide? Yes? |
I answered my own question. Yes, they're the same!
http://en.wikipedia.org/wiki/Nicotinamide |
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Tue Apr 24, 2012 4:48 pm |
Debb3485 wrote: |
DrJ wrote: |
Debb3485 wrote: |
DrJ, Thank you for your detailed analysis. I can certainly tell that you did a little research. You are correct as the literature I received says that Dr. Petrikovsky specializes in Fetal Physiology and performs in-utero surgery and that he surmised that something in Wharton Jelly caused the babies surgical sites to completely heal which lead to his discovery which isolated the peptide. The literature then says he was able to create a synthetic peptide that copies the chemical makeup of Wharton Jelly and that this peptide is named P199. So I would surmise that he developed P199 which Kate Somerville says is in Cytocell. I am certainly one who falls for marketing schemes and so I tend to be a serial skin care product purchaser. I am looking forward to getting the samples of the product you developed. The price doesn't bother me as I've bought La Mer, La Prairie, Sisley, Perricone, PTR, etc so if I see good results I will purchase and hopefully stay with the product for some time. But looking forward to more posts from you about your products as well as your analysis of other products in the market. |
Thanks Debb3485. Could you share the address or phone # on that brochure? Maybe we could take an even closer look, and call the company. Maybe there is new information. Always want to keep an open mind. |
DrJ, the phone number is 1-800-941-5905, customer service # is 888-232-1834 and there is a mailing address of 56 West 45th St, Suite 1001 New York, NY 10036. I'd be curious what else you find out about the product. Thank you! |
These are direct mail marketers. It sort of figures. No web site makes me very suspicious. I'll try calling & finding out more. |
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Tue Apr 24, 2012 5:29 pm |
DrJ
Quote: |
This reminds me a lot of the Amatokin story... Secret peptide THAT STIMULATES YOUR OWN STEM CELLS (bunk) from hidden labaoratory in former USSR surrounded by barbed wire fence (a prison maybe full of bunco artists?). |
Jom
Quote: |
Just for clarification purposes, Nicotinamide is the same as niacinamide? Yes? |
Yes. |
_________________ If you make, first do no harm, your Law, you will never strike the first blow and will be known as a man of peace who can fight like ten tigers, a Human in the act of Being. There is no greater rank than this. Ashida Kim on War.~Cellese~AnteAge Serum and Accelerator, DermaRoller ,MyFawnie AA2G serum, KNN G ForceUltrasound., SEA, ChrySun 25% ZnO |
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Tue Apr 24, 2012 5:38 pm |
No, I'm not talking about ingredients per se. My understanding was that Estee Lauder bought Dr. Yarosh, his research and his Remergent product and then marketed it as EL ANR.
Quote: |
WATCHING THE CLOCK
Clock genes and their function form a key part of the technology that has inspired the new Advanced Night Repair Synchronized Recovery Complex.
"In our lab, we have never given up on the idea of reversing wrinkles. We have leads and ideas, and continue to work on new technologies. I can’t tell you I can turn a 90-year old woman into a 30-year old woman today, but that doesn’t mean we aren’t trying or that it might never happen."
Dr Dan Yarosh, Senior Vice President, Research & Development, Basic Science Research, The Estée Lauder Companies
“Clock genes are a family of different genes that contribute to the timing and activation of the skin’s natural functioning, in particular, the repair processes,” explained Maes.
“These clocks can become more and more out of sync due to factors such as chronological ageing, stress and environmental assaults, which cause a “lag” in skin’s optimal functioning and decrease skin’s repair efficiency. We are among the first scientists to recognise the importance of supporting the synchronisation of these clock genes.”
Until recently, it was thought that all cellular synchronisation occurred through one “master clock”. New research now shows that every single skin cell contains its own clock genes, which help each cell to maximise its own DNA repair.
As its name suggests. Advanced Night Repair Synchronized Recovery Complex supports clock genes and the cells’ natural synchronisation process, thereby helping repair happen at the right time and at the optimum rate for maximum efficiency.
Maes added: “Many studies have now shown that at night skin’s activities are different. Night-time is the optimal time to support skin [repair] because it is not trying to fight off external aggressors, as it is during the day.”
This opinion is echoed by Dr Dan Yarosh, Senior Vice President, Research & Development, Basic Science Research, at The Estée Lauder Companies. Yarosh joined the group in 2008, and is charged with applying his expertise in molecular biology and DNA repair to create further innovative skincare technologies.
“There's a big advantage to having DNA repair occur at night,” he reiterated. “During the day, the DNA is being called upon to function and it's also absorbing environmental damage, particularly from the sunlight. At night it’s time for rest. It's when nutrients are most available; it's when the DNA is not competing with other functions; so DNA repair is best accomplished at night.”
Yarosh continued: “[Looking ahead] we are trying to understand how DNA fits in with all the other functions of the skin, and how DNA repair is called upon at different stages in the cell development so that the DNA is at its optimum health. I think we're going to learn in the future that DNA repair is related to many other cell functions that we hadn't imagined before.”
http://www.moodiereport.com/document.php?c_id=33&doc_id=20964 |
All I'm pointing out is that I was under the impression (possibly wrong) that Dr. Yarosh's research was ground-breaking and not just another moisturiser. As far as I can work out Dr Yarosh is still the Sr VP Basic Science Research at Estee Lauder.
DrJ - note also that Dr. Yarosh states that repair is best accomplished at night and I remember that you disagree with this assumption. |
_________________ Born 1950. There's a new cream on the market that gets rid of wrinkles - you smear it on the mirror!! |
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Tue Apr 24, 2012 6:10 pm |
Keliu wrote: |
No, I'm not talking about ingredients per se. My understanding was that Estee Lauder bought Dr. Yarosh, his research and his Remergent product and then marketed it as EL ANR.
Quote: |
WATCHING THE CLOCK
Clock genes and their function form a key part of the technology that has inspired the new Advanced Night Repair Synchronized Recovery Complex.
"In our lab, we have never given up on the idea of reversing wrinkles. We have leads and ideas, and continue to work on new technologies. I can’t tell you I can turn a 90-year old woman into a 30-year old woman today, but that doesn’t mean we aren’t trying or that it might never happen."
Dr Dan Yarosh, Senior Vice President, Research & Development, Basic Science Research, The Estée Lauder Companies
“Clock genes are a family of different genes that contribute to the timing and activation of the skin’s natural functioning, in particular, the repair processes,” explained Maes.
“These clocks can become more and more out of sync due to factors such as chronological ageing, stress and environmental assaults, which cause a “lag” in skin’s optimal functioning and decrease skin’s repair efficiency. We are among the first scientists to recognise the importance of supporting the synchronisation of these clock genes.”
Until recently, it was thought that all cellular synchronisation occurred through one “master clock”. New research now shows that every single skin cell contains its own clock genes, which help each cell to maximise its own DNA repair.
As its name suggests. Advanced Night Repair Synchronized Recovery Complex supports clock genes and the cells’ natural synchronisation process, thereby helping repair happen at the right time and at the optimum rate for maximum efficiency.
Maes added: “Many studies have now shown that at night skin’s activities are different. Night-time is the optimal time to support skin [repair] because it is not trying to fight off external aggressors, as it is during the day.”
This opinion is echoed by Dr Dan Yarosh, Senior Vice President, Research & Development, Basic Science Research, at The Estée Lauder Companies. Yarosh joined the group in 2008, and is charged with applying his expertise in molecular biology and DNA repair to create further innovative skincare technologies.
“There's a big advantage to having DNA repair occur at night,” he reiterated. “During the day, the DNA is being called upon to function and it's also absorbing environmental damage, particularly from the sunlight. At night it’s time for rest. It's when nutrients are most available; it's when the DNA is not competing with other functions; so DNA repair is best accomplished at night.”
Yarosh continued: “[Looking ahead] we are trying to understand how DNA fits in with all the other functions of the skin, and how DNA repair is called upon at different stages in the cell development so that the DNA is at its optimum health. I think we're going to learn in the future that DNA repair is related to many other cell functions that we hadn't imagined before.”
http://www.moodiereport.com/document.php?c_id=33&doc_id=20964 |
All I'm pointing out is that I was under the impression (possibly wrong) that Dr. Yarosh's research was ground-breaking and not just another moisturiser. As far as I can work out Dr Yarosh is still the Sr VP Basic Science Research at Estee Lauder.
DrJ - note also that Dr. Yarosh states that repair is best accomplished at night and I remember that you disagree with this assumption. |
Conditions may be more favorable for some types of repair at night (or simply in the dark) since there is less going on, but the same process are going on during the day as well. I want to see repair actives working 24/7. A lot of natural repair mechanisms are active during the day. We should take our cue from nature.
The funny thing about Dr Y's opinion is that if there is one good bit of logic about day/night cycles, it might be that DNA repair should go on during the day so that it can be accomplished right after the damage takes place. Why wait? I would want an enzyme that works to repair photodamage to be on sentry duty while the sun shines. |
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Tue Apr 24, 2012 6:11 pm |
Apologies if this has already been asked/covered, but what kind of delivery system is required for cytokines to be effective?
BTW, I ordered samples last night. |
_________________ No longer answering PM's due to numerous weird messages. |
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Tue Apr 24, 2012 7:04 pm |
bethany wrote: |
Apologies if this has already been asked/covered, but what kind of delivery system is required for cytokines to be effective?
BTW, I ordered samples last night. |
Bethany, the delivery system is by nanoliposomes. |
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Tue Apr 24, 2012 7:06 pm |
DrJ wrote: |
Conditions may be more favorable for some types of repair at night (or simply in the dark) since there is less going on, but the same process are going on during the day as well. I want to see repair actives working 24/7. A lot of natural repair mechanisms are active during the day. We should take our cue from nature.
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Dr. J, is it really a good idea to put actives on both day and night-shouldn't we give our skin a break from actives sometimes? And, are there different "levels" of actives. For example, would Retin A and BM-MSC be classified as high levels of actives (or the "most" active), are they in the same class? How would you classify active ingredients in terms of most active to least active? For example, you have retinol and soy isoflavones. Isn't the real "high" active ingredient the retinol and the mosre soothing less active ingredient the soy. As I'm typing this I'm thinking that maybe it depends on how you define active. Anyway, hopefully you get the gist of what I'm asking. Any thoughts? This is what I'm thinking of in terms of high to low actives starting with the highest (I'm just calling them high and low maybe there's another name for them):
Tretonin
Retinalhyde
Retinol
L-ascorbic acid
AHA's (just in general they can probably have a highest to lowest too)
Peptides
Niacinamide
Antioxidants (including all vitamins except A & C, yerba mate, soy isoflavones, coffeeberry, green tea, etc)
Not sure where BM-MSC fits in there.
I guess I'm just thinking that there are some actives that are more acidic (the high level ones) and some that are more soothing and is it a good idea to use all high level actives at one time of day and all more soothing actives another time of day or is it good to use high level actives both times of day to keep the juices flowing?
Do we ever want to give our skin a break and use a good basic moisturizer without any high level actives in it? Like EL ANR |
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Tue Apr 24, 2012 7:16 pm |
jom wrote: |
Do we ever want to give our skin a break and use a good basic moisturizer without any high level actives in it? Like EL ANR |
Why is EL ANR being referred to as just a basic moisturiser when all the research done by Dr. Yarosh claims that it repairs skin cells? |
_________________ Born 1950. There's a new cream on the market that gets rid of wrinkles - you smear it on the mirror!! |
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Tue Apr 24, 2012 7:24 pm |
Keliu wrote: |
jom wrote: |
Do we ever want to give our skin a break and use a good basic moisturizer without any high level actives in it? Like EL ANR |
Why is EL ANR being referred to as just a basic moisturiser when all the research done by Dr. Yarosh claims that it repairs skin cells? |
I was referring to Dr. J and DragoN's statements that it is just a good moisturizer. So I was just giving him a point of reference. I'm not aware of the research behind EL ANR how are skin cells supposed to be repaired with it? What is the active ingredient in it? |
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Tue Apr 24, 2012 7:49 pm |
jom wrote: |
Keliu wrote: |
jom wrote: |
Do we ever want to give our skin a break and use a good basic moisturizer without any high level actives in it? Like EL ANR |
Why is EL ANR being referred to as just a basic moisturiser when all the research done by Dr. Yarosh claims that it repairs skin cells? |
I was referring to Dr. J and DragoN's statements that it is just a good moisturizer. So I was just giving him a point of reference. I'm not aware of the research behind EL ANR how are skin cells supposed to be repaired with it? What is the active ingredient in it? |
Here's some blurb on Dr. Yarosh. He has been involved with DNA research for over 20 years. He is also the author of the book "The New Science of Perfect Skin" which has been discussed quite allot here. His product line, Remergent, was purchased by Estee Lauder some years ago and was then formulated under their brand name.
Quote: |
Dr. Yarosh, widely recognized as a pioneer in the science of DNA repair, is the author of more than 100 scientific papers and two dozen patents. He is an active participant in international photobiology societies and the New York biotechnology community.
AGI Dermatics, founded by Dr. Yarosh in 1985, has emerged as a world leader in DNA repair technology for skin and is best known for developing Dimericine®, a drug that is under clinical testing for treating patients with skin cancers and pre-cancers. AGI Dermatics is also the developer of Remergent, a doctor-dispensed skincare line based on the science of DNA repair.
http://www.evaluatepharma.com/Universal/View.aspx?type=Story&id=140241 |
I'm by no means a proponent of Dr. Yarosh - I tried the Remergent DNA Repair and wasn't that impressed. However, I AM currently using the EL ANR and like it very much. Don't know what the difference is between the two (if any) - although they are a totally different consistency.
But I am interested in how all of Dr. Yarosh's research (for which EL must have paid a pretty penny) can just be dismissed. |
_________________ Born 1950. There's a new cream on the market that gets rid of wrinkles - you smear it on the mirror!! |
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Tue Apr 24, 2012 8:17 pm |
Keliu wrote: |
Here's some blurb on Dr. Yarosh. He has been involved with DNA research for over 20 years. He is also the author of the book "The New Science of Perfect Skin" which has been discussed quite allot here. His product line, Remergent, was purchased by Estee Lauder some years ago and was then formulated under their brand name.
Quote: |
Dr. Yarosh, widely recognized as a pioneer in the science of DNA repair, is the author of more than 100 scientific papers and two dozen patents. He is an active participant in international photobiology societies and the New York biotechnology community.
AGI Dermatics, founded by Dr. Yarosh in 1985, has emerged as a world leader in DNA repair technology for skin and is best known for developing Dimericine®, a drug that is under clinical testing for treating patients with skin cancers and pre-cancers. AGI Dermatics is also the developer of Remergent, a doctor-dispensed skincare line based on the science of DNA repair.
http://www.evaluatepharma.com/Universal/View.aspx?type=Story&id=140241 |
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He was worth enough to EL to shut down his own line and go to work for them, so he must have some kind of knowledge!
One of my former Disney clients works for them now...I'll ping her tomorrow and see if maybe they can weigh in on their products here. |
_________________ No longer answering PM's due to numerous weird messages. |
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Tue Apr 24, 2012 8:44 pm |
bethany wrote: |
Keliu wrote: |
Here's some blurb on Dr. Yarosh. He has been involved with DNA research for over 20 years. He is also the author of the book "The New Science of Perfect Skin" which has been discussed quite allot here. His product line, Remergent, was purchased by Estee Lauder some years ago and was then formulated under their brand name.
Quote: |
Dr. Yarosh, widely recognized as a pioneer in the science of DNA repair, is the author of more than 100 scientific papers and two dozen patents. He is an active participant in international photobiology societies and the New York biotechnology community.
AGI Dermatics, founded by Dr. Yarosh in 1985, has emerged as a world leader in DNA repair technology for skin and is best known for developing Dimericine®, a drug that is under clinical testing for treating patients with skin cancers and pre-cancers. AGI Dermatics is also the developer of Remergent, a doctor-dispensed skincare line based on the science of DNA repair.
http://www.evaluatepharma.com/Universal/View.aspx?type=Story&id=140241 |
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He was worth enough to EL to shut down his own line and go to work for them, so he must have some kind of knowledge!
One of my former Disney clients works for them now...I'll ping her tomorrow and see if maybe they can weigh in on their products here. |
I started a new thread on DNA repair on the skin care and makeup forum maybe we can discuss it over there
http://www.essentialdayspa.com/forum/viewthread.php?tid=45459 |
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Wed Apr 25, 2012 12:01 am |
Dr.J and DragoN, What do you think of this moisturizer?
Water (Aqua), Helianthus Annuus (Sunflower) Seed Oil, Squalane, Butylene Glycol, Diglycerin, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Alcohol, Glycerin, C12-15 Alkyl Benzoate, Isopropyl Isostearate, Hexanoyl Dipeptide-3 Norleucine Acetate, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-5, Ceramide 2, Dipalmitoyl Hydroxyproline, Hydroxyphenyl Propamidobenzoic Acid, Epilobium Angustifolium Flower/Leaf/Stem Extract, Sodium Hyaluronate, Pyrus Malus (Apple) Fruit Extract, Glucosamine HCl, Bambusa Vulgaris Extract, Pisum Sativum (Pea) Extract, Soy Isoflavones, Hydrolyzed Soy Protein, Ursolic Acid, Ilomastat, Ubiquinone, Tocopheryl Acetate, Tocopherol, Panthenol, Olea Europaea (Olive) Leaf Extract, Camellia Oleifera (Green Tea) Leaf Extract, Lycium Barbarum (Goji) Fruit Extract, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Tribehenin, PEG-10 Rapeseed Sterol, Pentylene Glycol , Ceteareth-20, Steareth-2, Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Methylparaben, Propylparaben, Butylparaben, Isobutylparaben, Ethylparaben, Fragrance. |
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Wed Apr 25, 2012 1:44 am |
DrJ wrote: |
majorb wrote: |
Dr J - Just wondering if there's any chance that those of us from the UK who have a US shipping address but a UK billing address will be able to order from your site soon? At the moment, the billing addresses are set up only for the US, Australia and Canada. |
Let me look into that. Sounds like an easy fix. |
Hi again, Dr J.
Just wanted to let you know that the very helpful Steve has emailed me to say that he hopes UK billing addresses will be implemented on Wednesday. Fingers crossed as I'm very keen to give Ante Age a try.
Anyone else in the UK who has a US shipping address and who is waiting to order might like to try again after then. |
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Wed Apr 25, 2012 2:00 am |
@ Jom
Honestly?
Kitchen sink of actives at well below sub clinically effective levels, bolloxed together in a silicon feel good cross polymer mess.
Probably charging 60-75 US for it due to the cacophony of peptides.
If you held a gun to my head and forced a choice between that and EL? I would DIY it for better effect. |
_________________ If you make, first do no harm, your Law, you will never strike the first blow and will be known as a man of peace who can fight like ten tigers, a Human in the act of Being. There is no greater rank than this. Ashida Kim on War.~Cellese~AnteAge Serum and Accelerator, DermaRoller ,MyFawnie AA2G serum, KNN G ForceUltrasound., SEA, ChrySun 25% ZnO |
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Wed Apr 25, 2012 6:25 am |
DragoN wrote: |
@ Jom
Honestly?
Kitchen sink of actives at well below sub clinically effective levels |
Dragon, I am curious how you know the actives are well below sub clinical levels? I mean what gives that away? When looking at Dr J's formula, it also looks like a kitchen sink of actives that (if we didn't know by him telling us) would look well below clinical levels, right? So, how can you tell when actives are not in a product at the right levels? |
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Thu Mar 28, 2024 1:28 pm |
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