Review: Cellese AnteAGE Serum & Accelerator
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free skin care · Sat Jun 09, 2012 7:24 pm

Any thoughts on whether the anteage product might help with syringoma due to the cytokine action?
There have been discussions on this board before, but essentially, most dermatologists feel it is a benign condition where the laser/surgical "cures" may be worse than the condition itself.

free skin care · Sat Jun 09, 2012 8:44 pm

Alexya wrote:

Any thoughts on whether the anteage product might help with syringoma due to the cytokine action?
There have been discussions on this board before, but essentially, most dermatologists feel it is a benign condition where the laser/surgical "cures" may be worse than the condition itself.

Good question. We haven't heard any reports as of yet. So called eruptive syringomas may represent a hyperplastic response of the eccrine duct to an inflammatory reaction, so one could speculate potential benefit.

free skin care · Sat Jun 09, 2012 8:53 pm

DrJ wrote:

Alexya wrote:

Any thoughts on whether the anteage product might help with syringoma due to the cytokine action?
There have been discussions on this board before, but essentially, most dermatologists feel it is a benign condition where the laser/surgical "cures" may be worse than the condition itself.

Good question. We haven't heard any reports as of yet. So called eruptive syringomas may represent a hyperplastic response of the eccrine duct to an inflammatory reaction, so one could speculate potential benefit.

I'm still a little confused about the inflammation aspect. As I stated previously, I have sebaceous hyperplasia which I've pretty much got under control. But to my knowledge, I've never had any inflammation. Of course, it could be that there is something going on deep in the dermis - but wouldn't that be evident in some kind of redness or an an acne like response? I've been to numerous dermatologists about this condition and all say that it's either hereditory or caused simply by overactive oil glands - they never mentioned anything about inflammation.

free skin care · Sat Jun 09, 2012 9:10 pm

I changed my mind, and have decided to use the AnteAGE serum on my neck and chest for the remainder of the product. I have been doing so for 1 week now. I want to see if I get any improvement in this area, as my neck and chest are pretty bad looking. I have Poikiloderma of Civatte on my neck and it is not pretty. Will report when my bottles run out if this area has improved. I did take photos just in case and if I have improvement, I will post them.

free skin care · Sun Jun 10, 2012 6:27 am

rileygirl wrote:

I changed my mind, and have decided to use the AnteAGE serum on my neck and chest for the remainder of the product.

You are still using it on your face as well, right?

free skin care · Sun Jun 10, 2012 6:32 am

RussianSunshine wrote:

rileygirl wrote:

I changed my mind, and have decided to use the AnteAGE serum on my neck and chest for the remainder of the product.

You are still using it on your face as well, right?

No, not at the moment. I want to test it on my neck/chest and I honestly can't afford to use it in all areas. That would get too expensive. I also realized that the redness relief was not permanent (at least at this time in my usage of it) because as soon as I introduced something else, the redness returned.

free skin care · Sun Jun 10, 2012 6:56 am

rileygirl wrote:

No, not at the moment. I want to test it on my neck/chest and I honestly can't afford to use it in all areas. That would get too expensive. I also realized that the redness relief was not permanent (at least at this time in my usage of it) because as soon as I introduced something else, the redness returned.

I am not even dreaming about finding a topical that would reduce my redness permanently. May I ask what you introduced?

My hope with this product is that it will allow me to tolerate Retin A and Vit C. Do you think the serum will help me to achieve that?

free skin care · Sun Jun 10, 2012 7:01 am

RussianSunshine wrote:

I am not even dreaming about finding a topical that would reduce my redness permanently. May I ask what you introduced?

My hope with this product is that it will allow me to tolerate Retin A and Vit C. Do you think the serum will help me to achieve that?

I know. I need to give up on my dream of finding something permanent for the redness! I introduced the AVST.

It definitely may help, RussianSunshine. Really the only way to know is to give it a try!

free skin care · Sun Jun 10, 2012 7:32 am

rileygirl wrote:

Really the only way to know is to give it a try!

Yeah, I am waiting for it to come, as you can see, quite impatiently Very Happy

free skin care · Sun Jun 10, 2012 7:34 am

Wish I could share the whole paper. It's brilliant.

Stem Cell Res Ther. 2012 May 31;3(3):20.

Mesenchymal stem cell therapy for attenuation of scar formation during wound healing.
Jackson WM, Nesti LJ, Tuan RS.
Source

Center for Cellular and Molecular Engineering, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, 450 Technology Drive, Room 221, Pittsburgh, PA 15219, USA. tuanrocky@gmail.com.
Abstract

ABSTRACT: Scars are a consequence of cutaneous wound healing that can be both unsightly and detrimental to the function of the tissue. Scar tissue is generated by excessive deposition of extracellular matrix tissue by wound healing fibroblasts and myofibroblasts, and although it is inferior to the uninjured skin, it is able to restore integrity to the boundary between the body and its environment. Scarring is not a necessary process to repair the dermal tissues. Rather, scar tissue forms due to specific mechanisms that occur during the adult wound healing process and are modulated primarily by the inflammatory response at the site of injury. Adult tissue-derived mesenchymal stem cells, which participate in normal wound healing, are trophic mediators of tissue repair. These cells participate in attenuating inflammation in the wound and reprogramming the resident immune and wound healing cells to favor tissue regeneration and inhibit fibrotic tissue formation. As a result, these cells have been considered and tested as a likely candidate for a cellular therapy to promote scar-less wound healing. This review identifies specific mechanisms by which mesenchymal stem cells can limit tissue fibrosis and summarizes recent in vivo studies where these cells have been used successfully to limit scar formation.

Sun Jun 10, 2012 10:26 am

DrJ, would that include any hyperpigmentation that often (or in my case, always) presents with scarring? Thanks

free skin care · Sun Jun 10, 2012 2:54 pm

2dagym wrote:

DrJ, would that include any hyperpigmentation that often (or in my case, always) presents with scarring? Thanks

Yes. We are seeing results for hyperpigmentation from a variety of sources.

free skin care · Sun Jun 10, 2012 2:58 pm

We have spoken to dozens of device manufacturers in the last several days. We are turning heads with our rapid healing paradigm. Some already have clients who have reported very rapid healing, and amplified results.

free skin care · Sun Jun 10, 2012 3:11 pm

DrJ wrote:

We have spoken to dozens of device manufacturers in the last several days. We are turning heads with our rapid healing paradigm. Some already have clients who have reported very rapid healing, and amplified results.

Dr. J, when you talk about rapid healing what are you referring to. Like after a laser treatment,peel or dermarolling?

free skin care · Sun Jun 10, 2012 3:19 pm

CookieD wrote:

DrJ wrote:

We have spoken to dozens of device manufacturers in the last several days. We are turning heads with our rapid healing paradigm. Some already have clients who have reported very rapid healing, and amplified results.

Dr. J, when you talk about rapid healing what are you referring to. Like after a laser treatment,peel or dermarolling?

Laser, dermarolling primarily. We have some experience with peels as well, but because it is acid killing off surface layers of cells, we are find that AneAGE interferes - people aren't peeling with the usual doses. Its controlling the immune cells, not buffering the low pH of the acid. Some dermatologists are liking that because they can use stronger peels, working down to deeper layers. We are looking at the best timing to start AnteAGE after a peel. For laser and rolling its right away.

We are also looking at LED. That supposedly has a different mechanism of action, but the synergy makes sense.

free skin care · Sun Jun 10, 2012 4:19 pm

Report from IESCS, Day 2. A small army of estheticians wearing Truth Matters buttons, armed with knowledge about the difference between plant, fat, and mobile mesenchymal stem cells, abuzz about stem cytokines. Mission accomplished.

free skin care · Sun Jun 10, 2012 7:09 pm

DrJ wrote:

Report from IESCS, Day 2. A small army of estheticians wearing Truth Matters buttons, armed with knowledge about the difference between plant, fat, and mobile mesenchymal stem cells, abuzz about stem cytokines. Mission accomplished.

So happy for you Dr. J. Sounds like you had lots of fun. In this case lets hope what happens in Vegas doesn't stay in Vegas! What does IESCS stand for?

free skin care · Sun Jun 10, 2012 8:25 pm

DrJ wrote:

Report from IESCS, Day 2. A small army of estheticians wearing Truth Matters buttons, armed with knowledge about the difference between plant, fat, and mobile mesenchymal stem cells, abuzz about stem cytokines. Mission accomplished.

Did you have time to drop a quarter?

free skin care · Sun Jun 10, 2012 10:10 pm

jom wrote:

DrJ wrote:

Report from IESCS, Day 2. A small army of estheticians wearing Truth Matters buttons, armed with knowledge about the difference between plant, fat, and mobile mesenchymal stem cells, abuzz about stem cytokines. Mission accomplished.

So happy for you Dr. J. Sounds like you had lots of fun. In this case lets hope what happens in Vegas doesn't stay in Vegas! What does IESCS stand for?

International Esthetician Cosmetics and Spa Conference. Now I thought this was a sedate group, then I went up the escalator and found the salon portion. It was a carnival! Haircutting contests (amazing stagecraft, really entertaining, you have to see to believe). Wild & crazy. Dr J now knows what a brazilian is, having innocently stumbled into one being demonstrated. Well, it is Vegas. I guess there is a world beyond stem cells.

free skin care · Sun Jun 10, 2012 10:12 pm

Frodo wrote:

DrJ wrote:

Report from IESCS, Day 2. A small army of estheticians wearing Truth Matters buttons, armed with knowledge about the difference between plant, fat, and mobile mesenchymal stem cells, abuzz about stem cytokines. Mission accomplished.

Did you have time to drop a quarter?

Not yet~too busy!

free skin care · Sun Jun 10, 2012 10:37 pm

DrJ wrote:

International Esthetician Cosmetics and Spa Conference. Now I thought this was a sedate group, then I went up the escalator and found the salon portion. It was a carnival! Haircutting contests (amazing stagecraft, really entertaining, you have to see to believe). Wild & crazy. Dr J now knows what a brazilian is, having innocently stumbled into one being demonstrated. Well, it is Vegas. I guess there is a world beyond stem cells.

Thanks for making me laugh out loud when, yet again, insomnia rules. Laughing

free skin care · Sun Jun 10, 2012 10:47 pm

DrJ wrote:

jom wrote:

DrJ wrote:

Report from IESCS, Day 2. A small army of estheticians wearing Truth Matters buttons, armed with knowledge about the difference between plant, fat, and mobile mesenchymal stem cells, abuzz about stem cytokines. Mission accomplished.

So happy for you Dr. J. Sounds like you had lots of fun. In this case lets hope what happens in Vegas doesn't stay in Vegas! What does IESCS stand for?

International Esthetician Cosmetics and Spa Conference. Now I thought this was a sedate group, then I went up the escalator and found the salon portion. It was a carnival! Haircutting contests (amazing stagecraft, really entertaining, you have to see to believe). Wild & crazy. Dr J now knows what a brazilian is, having innocently stumbled into one being demonstrated. Well, it is Vegas. I guess there is a world beyond stem cells.

(If you could only see the picture in my mind) I guess you are having fun! Don't have TOO much! Laughing

free skin care · Mon Jun 11, 2012 5:22 am

This now has me curious as to the differences between spa/esthetician vs. cosmetic derms vs. cosmetic surgeon conferences in terms of exhibitors, presentations, etc.

Thanks for the reporting.

BFG

free skin care · Mon Jun 11, 2012 1:22 pm

Hey J,
Just checking in to see what happened with the sample issue. I was going to PM you but for some reason PM isn't working for me.
I got mine last week, as did my relative.
We live in different states.
Both of our sets of samples had just a very small dab of the product, less than the size of a quarter of a laptop key spread out, to give you a frame of reference. The samples didn't even cover the bottom of the container.
I wondered what was being done to correct this. I emailed customer service but have not heard back, so I thought I would write to you directly. I would really like to give the product a fair trial, as would my SIL.
Thanks.

free skin care · Mon Jun 11, 2012 2:56 pm

Ok, I got the serum today and paid $30 taxes. Holy crap.

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