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Mon Feb 21, 2005 9:47 am  |
I did a search and couldn't find any results for this, so sorry if this subject is pre-existing somewhere in the forum!!
I'm thinking about taking some coq10 supplements because of everything I've read about their antioxidant/anti-aging properties on top of being good for cellular respiration. The problem is, textbooks and articles I've read only state the main biological purpose of coq10, and I can't find *anything* on dosage amounts for skin health, or even if it's safe. I don't have any heart or other medical issues (I'm 25), so I was wondering if anyone has or is taking these supplements, if they're safe to the best of your knowledge, what's a recommended dose, and if it appears to make any difference? Most articles I've read don't have any definitive conclusion about their use as a supplement.
Thanks!! |
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Mon Feb 21, 2005 10:10 am |
Not sure if you saw this one:
Coenzyme Q10
Also known as ubiquinone, Co-Q10 is a naturally occurring vitaminlike compound that plays a role in cellular energy production. Although the body produces Co-Q10, after age 35 or 40 production rates drop resulting in insufficiencies that can impair optimal function. Often used to treat heart disease, Co-Q10’s antioxidant abilities are what prompted researchers to test its efficacy as a skin care ingredient.
In one study, Co-Q10 decreased the effects of skin tissue damage by lessening the effects of free radical molecules. In this placebo-controlled study, researchers found that after applying Co-Q10 daily to crow’s feet for six weeks, wrinkle depth was reduced by 27 percent; after 10 weeks, wrinkle depth was reduced by 43 percent. In the same study, researchers discovered the skin’s resistance to UV damage can be increased when CO-Q10 is applied.
Results of several studies also have shown that when topically applied to rat skin, Co-Q10 is readily absorbed. This is important, because although many compounds perform well in vitro, they must also be able to penetrate the skin to work.
I'm kinda bored just sitting here at home on the computer today - I will see what else I can dig up for you  |
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Mon Feb 21, 2005 10:55 am |
I take a coQ10 supplement which I believe is 100mg I didn't start it for my skin specifically and because I have started using lots of new products (thanks to this forum  ) I couldn't tell you whether it is responsible for any skin improvement. I take it more for general health purposes. Would be interested in anyone elses opinion. |
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Mon Feb 21, 2005 11:40 am |
kjb- Thanks for the info!! I think that's one of the articles/sites I had found the other day. That and everything else I've read sound great, and it makes me wonder what's better for the body as an antioxidant supplement: pomegranate, acai, grapeseed extract, or coq10.
If you find anything else, please share if you can!! |
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Mon Feb 21, 2005 11:46 am |
Not sure if any of this will help you or not.......I'm not even sure what half of it means 
"The processes of aging and photoaging are associated with an increase in cellular oxidation. This may be in part due to a decline in the levels of the endogenous cellular antioxidant coenzyme Q10 (ubiquinone, CoQ10). Therefore, we have investigated whether topical application of CoQ10 has the beneficial effect of preventing photoaging. We were able to demonstrate that CoQ10 penetrated into the viable layers of the epidermis and reduce the level of oxidation measured by weak photon emission. Furthermore, a reduction in wrinkle depth following CoQ10 application was also shown. CoQ10 was determined to be effective against UVA mediated oxidative stress in human keratinocytes in terms of thiol depletion, activation of specific phosphotyrosine kinases and prevention of oxidative DNA damage. CoQ10 was also able to significantly suppress the expression of collagenase in human dermal fibroblasts following UVA irradiation. These results indicate that CoQ10 has the efficacy to prevent many of the detrimental effects of photoaging.
Oxidative stress (UV irradiation, free radicals) plays a significant role in aging. Coenzyme Q10 (CoQ10) and exogenously applied antioxidants can significantly reduce the formation of oxidative stress with increasing age. In our in vitro and in vivo experiments concerning the parameters of ultraweak photon emission (UPE), intracellular thiol status, mitochondrial membrane potential and cell vitality, we demonstrated a diminished resistance in keratinocytes of old donors against UV irradiation. This reduced epidermal resistance against oxidative stressors, i.e. UV irradiation, can be improved by topical application of CoQ10 and antioxidants like alpha-glucosylrutin (15). Furthermore, our in vivo investigations show that wrinkles around the region of the eyes ("crow feet") could be reduced by long-term application of CoQ10."
Sounds promising, maybe would sound better if I could figure it out! |
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Mon Feb 21, 2005 2:04 pm |
This is taken from Dr. Perricone's Wrinkle Cure book (which btw was sent to me by the fabulous Cindi - thanks girl  )
Cooenzyme Q10
30-100mg daily under age 40.
100mg daily over age 40.
Consult your physician for dosages related to heart disease.
HTH
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Mon Feb 21, 2005 2:56 pm |
So you did read it then  |
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Mon Feb 21, 2005 7:51 pm |
I just started the Dr.Strauss
Herat drops, from every thing i have read about it, it is better and works the same way... Can get it at ALIVE
big bottle is 67.99
They are drops done here in B.C.
i was taking Q10 but will stop to see how this works,,,, LIZ |
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