The skin is the largest organ of the human body, and it maintains its own extensive immune system. The Reticulate of Langerhans Cells, which is the defense matrix of the epidermis, is essential to skin health. Langerhans Cells are white blood cells generated in the bone marrow that differentiate when they arrive in the epidermis, where they develop small legs, or dendrites. These are the skin’s guardians, programmed to induce an immune response when something they don’t recognize comes in contact with the skin. Ingredients that have been treated with bio-fermentation are accepted by the Langerhans Cells and readily assimilated into the epidermis, thereby preventing any cellular imbalance, which has been shown to generate free radicals and accelerate aging. By working in cooperation with the Langerhans Cells, IMMUNOCOLOGIE acts as a biocatalyst, reducing skin damage at a cellular level. In Bioferm, the Bio-Technical Fermentation Process unique to IMMUNOCOLOGIE, each ingredient is fermented in a special atmosphere and oxygen condition in order to ensure maximum efficacy. It is the first and only cosmetic formulation to use this technology.