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Flavia
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Wed Oct 26, 2011 4:53 pm      Reply with quote
Never mind responding to my last post about DMAE. There are already other discussions on this. Sorry!
RussianSunshine
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Wed Oct 26, 2011 4:54 pm      Reply with quote
Thank you for the link! Do you prefer it to the SkinBiology Lactic Power?

rileygirl wrote:
RussianSunshine wrote:
Which MD Forte creams are you referring to?



Hi RussianSunshine! They are the face creams in a jar and marked I, II, or III depending on the strength. I think I is plenty for most people.

Here is a link to the product just for the photo.
http://www.drugstore.com/m-d-forte-facial-cream-l-with-glycolic-acid/qxp68351?catid=98081
rileygirl
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Wed Oct 26, 2011 4:55 pm      Reply with quote
Flavia wrote:
Has anyone tried mixing DMAE powder with any of your creams? Is there enough research behind this? I've mixed it with CeraVe. Just wonderin' what your thoughts are and if you've seen results.


There is (or was?) controversy over DMAE. I use Skinbiology's Two Timing Tightener, which has this ingredient, but only occasionally, not on a daily basis. It definitely makes a temporary difference on my skin, but I still am not sure if it is "safe" or not.

Just in case you have not read this: http://www.smartskincare.com/ingredients/dmae_safety.html
Firefox7275
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Wed Oct 26, 2011 5:02 pm      Reply with quote
The problem with research on the efficacy of commercial topical products is that the studies are often biased from the outset, too short a duration to determine the long term results, and protocols are rarely rigorous enough to eliminate the 'placebo effect'.

In addition to what has already been posted ... research shows an anti-inflammatory/ stress relieving lifestyle can slow (and in some cases reverse) the ageing process. Do also consider the bare bones of your skincare routine since dehydration will make fine lines look worse, and it is known that cell repair and regeneration are most efficient when the tissues are hydrated. For cleansing sulphate surfactants are proven to be particularly drying; whereas lanolin, urea and low molecular weight hyaluronic acid are proven to be highly effective emollients/ humectants. You might also consider a light oil such as rosehip seed - which studies suggest has healing, anti inflammatory or anti ageing properties - either within your moisturising cream or as part of an antioxidant blend.

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rileygirl
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Wed Oct 26, 2011 5:39 pm      Reply with quote
RussianSunshine wrote:
Thank you for the link! Do you prefer it to the SkinBiology Lactic Power?



You're welcome! Very Happy I like the Skinbio LP10 for me at this time due to the fact that it has the other good ingredients in it, it is gentle on my skin, and seems to make my skin smooth feeling and moisturized all at once! However, MD Forte is a really good brand and I did what Glamcat did, worked my way up from I to III. I will say that when I used the MD Forte glycolic cream, it was the only time I can remember that my husband noticed my skin (in a good way!). Not sure if that helps you or not, RussianSunshine!
RussianSunshine
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Thu Oct 27, 2011 5:27 am      Reply with quote
Your recommendations always help. Wink I just ordered the Lactic Power, as I need some really gentle but powerful AHA product. Not single one has passed my test yet!

rileygirl wrote:


You're welcome! Very Happy I like the Skinbio LP10 for me at this time due to the fact that it has the other good ingredients in it, it is gentle on my skin, and seems to make my skin smooth feeling and moisturized all at once! However, MD Forte is a really good brand and I did what Glamcat did, worked my way up from I to III. I will say that when I used the MD Forte glycolic cream, it was the only time I can remember that my husband noticed my skin (in a good way!). Not sure if that helps you or not, RussianSunshine!
Flavia
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Thu Oct 27, 2011 7:00 am      Reply with quote
Is it necessary to use both Retin A and an AHA? Don't they accomplish the same thing?
RussianSunshine
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Thu Oct 27, 2011 11:52 am      Reply with quote
Flavia wrote:
Is it necessary to use both Retin A and an AHA? Don't they accomplish the same thing?


I don't think that AHAs are clinically proven to repair skin. My understanding is that their main function is to remove old skin cells.
Barefootgirl
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Thu Oct 27, 2011 12:46 pm      Reply with quote
At the risk of sounding self-important, if you search through many of my old posts, you will note that I only focus on anti-aging products or treatments with a fair amount of research to support them.

I have posted notes from my own research here, in particular - last year I provided highlights from Dr. Baumann's most recently Dermatology textbook - a textbook detailing which topicals, treatments etc. are worth the time and money.

Best of luck, BFG
Flavia
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Thu Oct 27, 2011 12:52 pm      Reply with quote
RussianSunshine wrote:
Flavia wrote:
Is it necessary to use both Retin A and an AHA? Don't they accomplish the same thing?


I don't think that AHAs are clinically proven to repair skin. My understanding is that their main function is to remove old skin cells.


Yes, I was thinking that since Retin A removes old skin cells there might be no point in adding an AHA.
Barefootgirl
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Thu Oct 27, 2011 12:53 pm      Reply with quote
The Baumman textbook is very clear about clinical studies and research - whether there is enough to recommend the product/gadget, etc.

On a side note, I was very disapppointed that Palovia will not release the details of its clinical studies behind the home use laser.

As a comparison- last time I looked, Sonicare has a link to their clinical studies so we can decide whether their products are worth our money.

These are challenging economic times. It's my observation that most of us need to be very careful about who we spend our money with.

bfg
rileygirl
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Thu Oct 27, 2011 2:21 pm      Reply with quote
Barefootgirl wrote:
At the risk of sounding self-important, if you search through many of my old posts, you will note that I only focus on anti-aging products or treatments with a fair amount of research to support them.

I have posted notes from my own research here, in particular - last year I provided highlights from Dr. Baumann's most recently Dermatology textbook - a textbook detailing which topicals, treatments etc. are worth the time and money.

Best of luck, BFG


Here is the link to BFG's thread on the dermatology textbook.

http://www.essentialdayspa.com/forum/viewthread.php?tid=39883&highlight=dermatology+textbook
RussianSunshine
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Thu Oct 27, 2011 3:41 pm      Reply with quote
Barefootgirl, you do not sound self-importnat at all, but the EDS forum search engine is pain in the neck!

rileygirl, thanks for the great link! Tons of info.


Barefootgirl wrote:
At the risk of sounding self-important, if you search through many of my old posts, you will note that I only focus on anti-aging products or treatments with a fair amount of research to support them.

I have posted notes from my own research here, in particular - last year I provided highlights from Dr. Baumann's most recently Dermatology textbook - a textbook detailing which topicals, treatments etc. are worth the time and money.

Best of luck, BFG
natefan87
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Mon Oct 31, 2011 7:29 pm      Reply with quote
I would recommend Paula's Choice.
carara69
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Wed Nov 02, 2011 12:06 am      Reply with quote
retin-a has given me the best results with fine line.. very noticable
cm5597
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Fri Nov 04, 2011 9:38 am      Reply with quote
In addition to other comments, I would say that there are a few natural ingredients, like Aloe and Rose Hip Seed Oil, that have been proven to improve the skin. For example, Aloe in particular increases the collagen content of the skin, particularly type III collagen (the 'youthful' collagen). PubMed is a wealth of information to see how 'proven' things are:
http://www.ncbi.nlm.nih.gov/pubmed/

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RussianSunshine
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Fri Nov 04, 2011 4:00 pm      Reply with quote
Wow, I am surprised to find out that Aloe can have an effect on collagen. I thought it is only good for calming the skin.

cm5597 wrote:
In addition to other comments, I would say that there are a few natural ingredients, like Aloe and Rose Hip Seed Oil, that have been proven to improve the skin. For example, Aloe in particular increases the collagen content of the skin, particularly type III collagen (the 'youthful' collagen). PubMed is a wealth of information to see how 'proven' things are:
http://www.ncbi.nlm.nih.gov/pubmed/
rileygirl
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Fri Nov 04, 2011 5:45 pm      Reply with quote
cm5597 wrote:
In addition to other comments, I would say that there are a few natural ingredients, like Aloe and Rose Hip Seed Oil, that have been proven to improve the skin. For example, Aloe in particular increases the collagen content of the skin, particularly type III collagen (the 'youthful' collagen). PubMed is a wealth of information to see how 'proven' things are:
http://www.ncbi.nlm.nih.gov/pubmed/


cm5597, can you provide a link on the aloe vera and type III collagen?

I could only find this, which talks about Internal supplementation with aloe vera.

http://www.ncbi.nlm.nih.gov/pubmed/20548848
cm5597
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Sat Nov 05, 2011 7:55 pm      Reply with quote
rileygirl wrote:
cm5597 wrote:
In addition to other comments, I would say that there are a few natural ingredients, like Aloe and Rose Hip Seed Oil, that have been proven to improve the skin. For example, Aloe in particular increases the collagen content of the skin, particularly type III collagen (the 'youthful' collagen). PubMed is a wealth of information to see how 'proven' things are:
http://www.ncbi.nlm.nih.gov/pubmed/


cm5597, can you provide a link on the aloe vera and type III collagen?

I could only find this, which talks about Internal supplementation with aloe vera.

http://www.ncbi.nlm.nih.gov/pubmed/20548848



Huh, I thought I had seen a few papers on this, but it was a while ago, so maybe there were only a couple.

Here's one:

* http://www.ncbi.nlm.nih.gov/pubmed/9562243
(here's a paper on the differential effect of aloe on type I and type III collagen)


Try this search query in Google:

"aloe collagen type III OR 3 OR 111 site:www.ncbi.nlm.nih.gov/pubmed/" (remove quotation marks)

That pulls up 13 hits.

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34 y.o. FlexEffect and massage. Love experimenting with DIY and botanical skin care products. Appreciate both hard science and natural approaches. Eat green smoothies + lots of raw fruit and veggies.
cm5597
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Sat Nov 05, 2011 7:59 pm      Reply with quote
But here are some other peer-reviewed papers on the benefits of aloe for the skin. So I'd personally consider the science out there to be in favor of aloe.

For example,

* http://www.ncbi.nlm.nih.gov/pubmed/20548848
Dietary aloe reduces facial wrinkles and improves skin elasticity, as well as increasing the expression of a collagen gene

* http://www.ncbi.nlm.nih.gov/pubmed/19915322
Aloe enhances proliferation and collagen synthesis in human skin

* http://www.ncbi.nlm.nih.gov/pubmed/9854430
Aloe increases collagen turnover

* http://www.ncbi.nlm.nih.gov/pubmed/19409414
Aloe causes skin fibroblasts to proliferate

* http://www.ncbi.nlm.nih.gov/pubmed/10808702
Aloe reduces inflammation and promotes wound healing

* http://www.ncbi.nlm.nih.gov/pubmed/9562243
Aloe differentially stimulates type I and type III collagen

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Lacy53
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Sat Nov 05, 2011 8:41 pm      Reply with quote
Don't overlook this one CM:

http://www.ncbi.nlm.nih.gov/pubmed/21031007

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rileygirl
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Sat Nov 05, 2011 8:49 pm      Reply with quote
cm5597 wrote:
But here are some other peer-reviewed papers on the benefits of aloe for the skin. So I'd personally consider the science out there to be in favor of aloe.

For example,

* http://www.ncbi.nlm.nih.gov/pubmed/20548848
Dietary aloe reduces facial wrinkles and improves skin elasticity, as well as increasing the expression of a collagen gene

* http://www.ncbi.nlm.nih.gov/pubmed/19915322
Aloe enhances proliferation and collagen synthesis in human skin

* http://www.ncbi.nlm.nih.gov/pubmed/9854430
Aloe increases collagen turnover

* http://www.ncbi.nlm.nih.gov/pubmed/19409414
Aloe causes skin fibroblasts to proliferate

* http://www.ncbi.nlm.nih.gov/pubmed/10808702
Aloe reduces inflammation and promotes wound healing

* http://www.ncbi.nlm.nih.gov/pubmed/9562243
Aloe differentially stimulates type I and type III collagen


Thanks for the links, CM! I have not read them all, but of those that I did read, a lot seem to focus on wound repair (same thing as with the copper peptides), and I still am not convinced that repairing a wound is the same as repairing a wrinkle. (That said, I am trying copper peptides!)
cm5597
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Sat Nov 05, 2011 8:55 pm      Reply with quote
rileygirl wrote:
I still am not convinced that repairing a wound is the same as repairing a wrinkle. (That said, I am trying copper peptides!)


This is a very good point, and I take your point. It is a weakness of some of the articles I posted and much/most of the articles on aloe. I guess the things are more compelling to me are the alleviation of inflammation (which we all have to some degree), the seemingly beneficial effects on collagen in general, and the decrease in wrinkles in that oral supplementation study.

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cm5597
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Sat Nov 05, 2011 9:03 pm      Reply with quote
Lacy53 wrote:
Don't overlook this one CM:

http://www.ncbi.nlm.nih.gov/pubmed/21031007


Not overlooking anything. I'm not an expert on aloe and have only looked at several papers on aloe, not the full body of literature on aloe. I did see two other papers that show that aloe did not lead to neoplastic growth (so a ratio of 2:1 for the papers I've personally seen), although this paper suggests that in a few instances, it may lead to weak effects. Hence I did not comment on its neoplastic risk either way.

The one caveat that needs to be added is that mice are nocturnal animals, so I am always more skeptical of any study done on mice where they photodamage the mice and then try to extrapolate the results to humans.

Nonetheless, I totally agree with you that it is an important question to address for anything that enhances cell proliferation.

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rileygirl
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Sun Nov 06, 2011 7:15 am      Reply with quote
cm5597 wrote:


This is a very good point, and I take your point. It is a weakness of some of the articles I posted and much/most of the articles on aloe. I guess the things are more compelling to me are the alleviation of inflammation (which we all have to some degree), the seemingly beneficial effects on collagen in general, and the decrease in wrinkles in that oral supplementation study.


Yes, agree, we do all have some form of inflammation. I am interested in the oral supplementation and will definitely look into that. Do you take aloe vera internally, CM?
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