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DMAE again
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Uno
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Tue Apr 22, 2008 7:40 am      Reply with quote
Just wonder if anyone has heard any safety update on DMAE?

I have stopped using it for half n year already... was thinking if I should pick it up again. Laughing
Alley
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Tue Apr 22, 2008 7:52 am      Reply with quote
http://www.essentialdayspa.com/forum/viewthread.php?tid=28429&postdays=0&postorder=asc&highlight=dmae&start=25

Uno here is a thread from a little while ago, I think there is some useful info

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senesce
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Wed May 14, 2008 5:28 pm      Reply with quote
In short term, you see the result.

In long term, it may damage your skin.

So IMO, no no and never use it.
bushy
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Fri May 16, 2008 3:05 am      Reply with quote
Uno wrote:
Just wonder if anyone has heard any safety update on DMAE?

I have stopped using it for half n year already... was thinking if I should pick it up again. Laughing


I have read some research that disputes the original manufacturer claims in that it has no beneficial effect on the skin. You can make up your own mind but for me, I think there are far better products available.

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Fri May 16, 2008 3:43 am      Reply with quote
bushy wrote:
Uno wrote:
Just wonder if anyone has heard any safety update on DMAE?

I have stopped using it for half n year already... was thinking if I should pick it up again. Laughing


I have read some research that disputes the original manufacturer claims in that it has no beneficial effect on the skin. You can make up your own mind but for me, I think there are far better products available.


Hi bushy,
will you share with us the products you think are better. Thanks Lou
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Fri May 16, 2008 4:59 am      Reply with quote
senesce wrote:
In short term, you see the result.

In long term, it may damage your skin.

So IMO, no no and never use it.


Hello, senesce.

I have read your posts and would love to hear what skin care products you use.

Do you have any recommendations?

TIA. Smile

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bushy
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Sat May 17, 2008 12:53 am      Reply with quote
Loumomofthree wrote:


Hi bushy,
will you share with us the products you think are better. Thanks Lou


If you let me know why you specifically wanted to use dmae or what benefits you are trying to achieve, then I may be able to suggest some alternatives.

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Sat May 17, 2008 12:58 am      Reply with quote
senesce wrote:
In short term, you see the result.

In long term, it may damage your skin.

So IMO, no no and never use it.


One study I read theorized the plumping effect was due to the cells swelling with water before they died.
racheli
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Fri Jun 06, 2008 7:15 am      Reply with quote
edenfield wrote:
senesce wrote:
In short term, you see the result.

In long term, it may damage your skin.

So IMO, no no and never use it.


One study I read theorized the plumping effect was due to the cells swelling with water before they died.



yes, this i read, too, and it concerns me as well...

but - does it need a special (over-)dose to make the cell die?
or will the cell die by any contact of dmae?
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Fri Jun 06, 2008 8:04 pm      Reply with quote
[quote="racheli
but - does it need a special (over-)dose to make the cell die?
or will the cell die by any contact of dmae?[/quote]

The studies I've read have indicated that cell destruction occurred with DMAE at 3% or higher.. These studies were performed on animal skin, and human skin recently excised during surgeries.

In short, the DMAE penetrated the layers of skin, reaches and penetrates the cells, the cells swell and eventually rupture and die.

This is why the folks who use these creams experience a fairly immediate plumping + tightening, but it is always temporary. And so this cycle continues, with each and every application. The real problem will not be apparent until the aging process can't keep up with producing enough cells to replace the ones that have died. That is when the proverbial s-it will hit the fan, and the face will sag irreparably.

You can read much more on the thread Alley recommended above.

I would just like to really say to everyone to make sure you thoroughly research every single thing you put on your skin.. So much of it is absorbed into the cells and bloodstream, and just because a manufacturer says it's wonderful, doesn't mean it's so.

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♥I'm flattered by all the lovely PM's, but I don't get here much these days. Please don't be afraid to post your quearies to other DIY members who will be glad to help you (or sell you their wares..lol) Still happy with LED, dermarolling and a DIY antioxidant regime. Peace & Hugs to all.♥
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Fri Jun 06, 2008 9:03 pm      Reply with quote
edenfield wrote:
senesce wrote:
In short term, you see the result.

In long term, it may damage your skin.

So IMO, no no and never use it.


One study I read theorized the plumping effect was due to the cells swelling with water before they died.


I also read this in my Biology course book. Our prof gave us a very long speech about the danger of using it.

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racheli
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Fri Jun 06, 2008 11:05 pm      Reply with quote
Kassy_A wrote:
The studies I've read have indicated that cell destruction occurred with DMAE at 3% or higher.. These studies were performed on animal skin, and human skin recently excised during surgeries.

In short, the DMAE penetrated the layers of skin, reaches and penetrates the cells, the cells swell and eventually rupture and die.

This is why the folks who use these creams experience a fairly immediate plumping + tightening, but it is always temporary. And so this cycle continues, with each and every application. The real problem will not be apparent until the aging process can't keep up with producing enough cells to replace the ones that have died. That is when the proverbial s-it will hit the fan, and the face will sag irreparably.

You can read much more on the thread Alley recommended above.

I would just like to really say to everyone to make sure you thoroughly research every single thing you put on your skin.. So much of it is absorbed into the cells and bloodstream, and just because a manufacturer says it's wonderful, doesn't mean it's so.


thanks for your reply, kassy..i agree with you..
i found it rather shocking too, that obviously manufacturers are putting (new) stuff into mixtures, which they dont have really information on..or - that they obviously care so little about the long-term side effects...

at least, when buying something i put onto my face, i would have trusted, not to kill my skin with it..!
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Tue Jun 10, 2008 11:36 pm      Reply with quote
According to the Daniel Yarosh book, DMAE is supposed to be a neurotransmitter and stimulates the nerve endings in the cells so that they contract and cause a mini facelift. But he goes on to say that in many cases it is mixed with a muscle relaxant which does not make sense as they would be working opposite to each other. He does not have any negative comments other than there is no reliable research that indicates DMAE works.

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edenfield
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Wed Jun 11, 2008 1:38 am      Reply with quote
DMAE is not a neurotransmitter itself, but it is a precusor for Acetylcholine
bushy
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Thu Jun 12, 2008 3:19 am      Reply with quote
edenfield wrote:
DMAE is not a neurotransmitter itself, but it is a precusor for Acetylcholine


Not quite correct. It is claimed that it stimulates nerve cells to release acetylcholine and Johnson & Johnson who market DMAE claim it is a neurotransmitter which supposedly alters nerve sensations. A neurometer has been used to test its claims.

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Kassy_A
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Mon Jun 16, 2008 11:04 pm      Reply with quote
Lots of interesting information on skincare can be found here, including a good explanation of what DMAE does to the cells;


http://www.truthinskincare.com/2008/01/pay-attention-truth-behind-trends-dmae_31.html

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♥I'm flattered by all the lovely PM's, but I don't get here much these days. Please don't be afraid to post your quearies to other DIY members who will be glad to help you (or sell you their wares..lol) Still happy with LED, dermarolling and a DIY antioxidant regime. Peace & Hugs to all.♥
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