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Wed May 28, 2008 1:31 pm  |
There have been some questions on this forum lately about Retin-A (tretinoin) and thinner skin as a possible unwanted effect from long term use. Being a Retin-A debutant myself I would like to know if this is a risk.
Scientific studies back up the claims that Retin-A is capable of reverse signs of aging by erasing fine lines and increasing collagen production in the dermis. Retin-A has been offered as an anti-aging on prescription for nearly 30 years, and no other skin care product has got similar scientific backing.
The initial side effects are redness, irritation and flakiness. As no studies on possible side effects of long term use have been accomplished, I have not been able to find any warnings from medical expertise about long term/permanent thinning and fragility of the skin from Retin-A.
On the contrary, dermatologists are frequently recommending and prescribing tretinoin for anti-aging purposes, and FDA trials suggests that you can continue to use Retin-A for a lifetime to maintain the benefits.
I have read numerous testimonials both on this and other forums from long term users who are very satisfied and told this cream has taken years off their face. BUT some users have experienced thinner, more fragile skin from the use of Retin-A. The cream works by increasing cell turnover and thinning the few top layers of the skin. Collagen production increases and thickens the inner layers of the skin. I have been wondering how a proven collagen builder can cause thin and fragile skin in some women's skin.
I found this review on Smartskincare from a woman who experienced thinner skin and more wrinkles after one month of use. Perhaps she has got a point in this review (quote):
While some skin may answer the call for repair, low levels of Human Growth Hormone and other chemicals important to skin growth may be limited in older and damaged skin. So in the end, thinning the skin may not result in creation of new collagen - just thin skin. And thin skin wrinkles easily.
http://www.smartskincare.com/reviews/product/antiaging_cream_na_retin-a_20040105.html
The women on EDS forum who have been combining Retin-A with dermarolling (collagen-induction therapy with needles) have generally reported great results as thicker skin and less wrinkles. I intend to choose this route as it seems to be a winning combination.
Any views on these theories? Any input is appreciated.  |
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Female, 40, Norway. Normal/dry skin, starting to see signs of aging. Staples: Glycolic acid cleanser, SkinCeuticals Phloretin CF, Revaleskin, NIA24. |
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