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Sat Feb 07, 2009 3:11 pm  |
I'm not sure that anyone can give assurances on the safety of EGFs. There's certainly considerable evidence of their involvement in some forms of cancer. See http://theoncologist.alphamedpress.org/cgi/content/full/8/5/496 for a reader-friendly discussion of this. Tyrosine kinase inhibitors--Gleevec is probably the most famous--block certain forms of cancer cells by interrupting the EGF triggered cascade of uncontrolled cell proliferation.
Now, just because some cancers may either start or be escalated by EGF naturally does not necessarily mean that exposing non-cancerous tissue to extra EGF will likewise result in cancer. But I think it is fair to say that it is a possibility, based on the mechanisms we currently know about, and that it has not been used cosmetically for long enough to demonstrate its safety.
For me, the risk versus benefit calculations make EGF cosmeteuticals not worth it. Others may differ, of course. |
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| Wed Apr 24, 2024 6:07 pm |
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