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Oxidized Ascorbic Acid
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rmc7
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Thu Jul 28, 2011 5:50 pm      Reply with quote
rileygirl wrote:
rmc7 wrote:
I will buy it. At least you believe in it enough to take the time to come
here and defend and
explain to some very
tough women who
understand the science
behind Skin Care.


rmc7, I am curious if you ever did buy this and what your thoughts are on it?


I recieved ReCverin yesterday, and used it this morning for the first time. I mixed afew drops with water then covered my face and neck,rubbed the rest into my hands. About 2o'clock i reached for my hand cream (a habit) i then looked at my hands and was astonished to see these well hydrated hands looking back at me! Coincidence? Maybe,but i will keep an eye on any changes and report back.

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Thu Jul 28, 2011 7:49 pm      Reply with quote
Thanks for the initial report, rmc7! Which "version" did you get?
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Fri Jul 29, 2011 4:44 pm      Reply with quote
rileygirl wrote:
Thanks for the initial report, rmc7! Which "version" did you get?


I got the 50/50. I am going to have my hubby take pix of these old wrinkley,sun damaged, liver spotted hands. We'll take a good at the results in about a mounth.

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NicoleCook
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Wed Aug 17, 2011 3:13 am      Reply with quote
Hi rmc7. I’m wondering how it feels on your skin? Is it sticky or greasy? I’m interested in how it works for your hands too, thanks in advance for posting your results!
ReCverin
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Sun Jun 17, 2012 10:39 am      Reply with quote
An interesting new study shows that dehydroascorbic acid permeates the stratum corneum at a rate 12 times faster than l-ascorbic acid.
http://www.researchgate.net/publication/225274699_Topical_Dehydroascorbic_Acid_%28Oxidized_Vitamin_C%29_Permeates_Stratum_Corneum_More_Rapidly_Than_Ascorbic_Acid.htm
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Sun Jun 17, 2012 1:31 pm      Reply with quote
ReCverin wrote:
An interesting new study shows that dehydroascorbic acid permeates the stratum corneum at a rate 12 times faster than l-ascorbic acid.
http://www.researchgate.net/publication/225274699_Topical_Dehydroascorbic_Acid_%28Oxidized_Vitamin_C%29_Permeates_Stratum_Corneum_More_Rapidly_Than_Ascorbic_Acid.htm


LOL. ReCverin,

The URL never works for me either so here is that link.

http://www.researchgate.net/publication/225274699_Topical_Dehydroascorbic_Acid_

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ReCverin
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Sun Jun 17, 2012 3:12 pm      Reply with quote
DarkMoon wrote:

LOL. ReCverin,

The URL never works for me either so here is that link.

http://www.researchgate.net/publication/225274699_Topical_Dehydroascorbic_Acid_


Thanks for posting a link that works!
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Sun Jun 17, 2012 3:17 pm      Reply with quote
ReCverin wrote:
DarkMoon wrote:

LOL. ReCverin,

The URL never works for me either so here is that link.

http://www.researchgate.net/publication/225274699_Topical_Dehydroascorbic_Acid_


Thanks for posting a link that works!


You are very welcome ReCverin Smile

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DarkMoon
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Mon Jun 18, 2012 10:15 am      Reply with quote
What happened to the sample sizes? None shown on the site anymore, only rmc7 tried it and never reported back? hmm

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ReCverin
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Tue Jun 19, 2012 5:35 am      Reply with quote
DarkMoon wrote:
What happened to the sample sizes? None shown on the site anymore...

The trial size we introduced last summer was a good idea, but it was never as successful a promotion as we had hoped. Our decision to market ReCverin 50/50 not only for skin care but also as a dietary supplement involved significant labeling and other changes in order to be compliant with the more rigid FDA requirements. These costly changes would also have been necessary for the trial size, and so we had to make the difficult decision to discontinue these Crying or Very sad.

The good thing is that ReCverin 50/50 is now a much more versatile product with uses beyond skin care. Most people don't realize that dehydroascorbic acid is a form of vitamin C found in considerable amounts in a natural diet; but unless they consume a lot of fresh, raw vegetables, they probably don't get very much in their modern diet. In addition, the most rapidly absorbed form of vitamin C is now available for direct application to the lips, mouth and throat, as well as the skin!
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Tue Jun 19, 2012 8:33 am      Reply with quote
ReCverin wrote:
DarkMoon wrote:
What happened to the sample sizes? None shown on the site anymore...

The trial size we introduced last summer was a good idea, but it was never as successful a promotion as we had hoped. Our decision to market ReCverin 50/50 not only for skin care but also as a dietary supplement involved significant labeling and other changes in order to be compliant with the more rigid FDA requirements. These costly changes would also have been necessary for the trial size, and so we had to make the difficult decision to discontinue these Crying or Very sad.

The good thing is that ReCverin 50/50 is now a much more versatile product with uses beyond skin care. Most people don't realize that dehydroascorbic acid is a form of vitamin C found in considerable amounts in a natural diet; but unless they consume a lot of fresh, raw vegetables, they probably don't get very much in their modern diet. In addition, the most rapidly absorbed form of vitamin C is now available for direct application to the lips, mouth and throat, as well as the skin!


Thank you for the honest explanation ReCverin! Smile

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Thu Aug 16, 2012 6:02 pm      Reply with quote
rmc7 wrote:
rileygirl wrote:
Thanks for the initial report, rmc7! Which "version" did you get?


I got the 50/50. I am going to have my hubby take pix of these old wrinkley,sun damaged, liver spotted hands. We'll take a good at the results in about a mounth.


rmc7,

How did the test go? Did you see good results with the product?

Anyone else test it out?

Thanks! Smile

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ReCverin
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Tue Dec 04, 2012 12:59 pm      Reply with quote
United States patent number 8,324,269, which covers dehydroascorbic acid solutions used for skin care and other purposes, issued today Dec. 4, 2012.
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Mon Aug 05, 2013 5:24 pm      Reply with quote
While most of the world continues to believe the old myth that oxidized vitamin C is bad for you, scientists continue to make remarkable discoveries about the benefits of dehydroascorbic acid! Published just months ago in the Journal of Nutritional Biochemistry is a study demonstrating that dehydroascorbic acid is superior to the common form of vitamin C (l-ascorbic acid) in fighting free radicals and reactive oxygen species.

“Exposure of U937 cells (human) to low micromolar levels of ascorbic acid or dehydroascorbic acid, while resulting in identical ascorbic acid accumulation, is unexpectedly associated with remarkably different responses to exogenous oxidants. We observed that otherwise nontoxic levels of hydrogen peroxide, tert-butylhydroperoxide or peroxynitrite promote toxicity in cells preloaded with ascorbic acid, whereas hardly any effect was detected in cells pretreated with dehydroascorbic acid.”

You can read the abstract and gain access to the full-text of the study here:
http://www.jnutbio.com/article/S0955-2863%2812%2900041-1/abstract J Nutr Biochem. 2013 Feb;24(2):467-74
Kassy_A
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Mon Aug 05, 2013 7:01 pm      Reply with quote
Perhaps "dehydroascorbic acid"has it's place in the nutritional/supplement market, but this is a skincare forum.

Like it or not, the ONLY form of vitamin C that has been PROVEN to generate collagen synthesis is L-Ascorbid Acid. Likewise, L-AA is the only molecular structure that has been PROVEN to penetrate the skin, and neutralize free radicals.

Good Vitamin C info here;

http://www.skininc.com/skinscience/ingredients/Keys-to-Unlocking-the-Benefits-of-Vitamin-C-181434171.html

A study published by the American Society for Dermatologic Surgery demonstrated that L-ascorbic acid, which is true vitamin C, is the chemical derivative of vitamin C that is chemically reactive and bioavailable. Other derivatives of vitamin C, including magnesium ascorbyl phosphate, ascorbyl-6-palmitate and dehydroascorbic acid, did not increase skin levels of L-ascorbic acid.

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♥I'm flattered by all the lovely PM's, but I don't get here much these days. Please don't be afraid to post your quearies to other DIY members who will be glad to help you (or sell you their wares..lol) Still happy with LED, dermarolling and a DIY antioxidant regime. Peace & Hugs to all.♥
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Tue Aug 06, 2013 1:44 am      Reply with quote
Kassy_A wrote:
Derivatives of vitamin C, including magnesium ascorbyl phosphate, ascorbyl-6-palmitate and dehydroascorbic acid, did not increase skin levels of L-ascorbic acid.


Dear Kassy,

A Yorkshire pig is pink, essentially hairless, and susceptible to sunburn, like a human. It therefore has been used as an animal model in sunburn and other skin studies. Unlike a human or a guinea pig, however, a Yorkshire pig is able to synthesize its own vitamin C.

In 2001, a study that is now very famous was published, which characterized vitamin C formulations for best absorption. That study was conducted on Yorkshire pigs. The statement quoted above, that you found on a commercial website, originally comes from that famous study.

The ability to absorb and utilize dehydroascorbic acid is found only in those species, such as humans, that cannot synthesize vitamin C. This ability is believed to be an adaptation to the genetic mutation that made us unable to make vitamin C in the first place. It allows us to recycle vitamin C, to use each molecule many times, and to stay alive even though we generally get a relatively small amount of vitamin C in our diet. These facts were apparently unknown to the authors of that famous study. So they undertook to test the absorption of dehydroascorbic acid in their animals. It is no surprise that they found no increase in the amount of ascorbic acid in the skin of Yorkshire pigs by applying dehydroascorbic acid, because those pigs are unable to absorb it into their cells.

The lead author of that famous study was Dr. Sheldon Pinnell, who passed away very recently. He is generally recognized as the pioneer in the use of vitamin C in skin care. A son of his is a founder of SkinCeuticals, the company that introduced the original CEF serum.

Although you consider dehydroascorbic acid to be impertinent in skin care, Dr. Pinnell certainly didn’t...otherwise he wouldn’t have tested it. And if he had chosen an appropriate animal model, perhaps his son’s company would have pursued a dehydroascorbic acid serum.

Unless I’m mistaken, you are the same Kassy who has gained some notoriety of her own by creating DIY recipes to mimic the original CEF serum of SkinCeuticals. If you are that same Kassy, then I’m surprised that you seem oblivious to the facts I’ve presented here, and to the current state of the science of vitamin C in general. If you want to be well-informed and knowledgeable, I’d suggest you start by getting your information by reading original, peer-reviewed scientific studies rather than commercial websites.
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Tue Aug 06, 2013 9:24 am      Reply with quote
ReCverin,

Thanks for this discussion...very enlightening!

I'm curious about using copper peptides with L-AA. We've been told not to use them together because the CP's will "inactivate" the vitamin C.
Though this is apparently true in the test tube, many people have reported excellent results using them together.
I'm speculating that the vitamin C is actually oxidized by the CPs and perhaps this is a good thing, given the information you've given us about DHAA?

Are you able or willing to elaborate on this for us?
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Tue Aug 06, 2013 12:06 pm      Reply with quote
I also enjoy reading this thread and am finding the discussions 'enlightening'. I would also like to know about the use of this with CPs. Additionally - could this be used after a dermaroll? Regular Vit C serums sting the skin quite a bit.

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Tue Aug 06, 2013 12:44 pm      Reply with quote
ReCverin wrote:
Kassy_A wrote:
Derivatives of vitamin C, including magnesium ascorbyl phosphate, ascorbyl-6-palmitate and dehydroascorbic acid, did not increase skin levels of L-ascorbic acid.


Unless I’m mistaken, you are the same Kassy who has gained some notoriety of her own by creating DIY recipes to mimic the original CEF serum of SkinCeuticals. If you are that same Kassy, then I’m surprised that you seem oblivious to the facts I’ve presented here, and to the current state of the science of vitamin C in general. If you want to be well-informed and knowledgeable, I’d suggest you start by getting your information by reading original, peer-reviewed scientific studies rather than commercial websites.


wow! no wonder for this snarky comment as it comes from someone who is likely to lose $ because of Kassy's recipes.... many have benefited from her recipes...

I ll never pay skinceutical or any other company for any ascorbic acid products, please... i can make my owm in less than 5 minutes, throw in some ferulic, acid, vita E, Phloretin too! minus the ton of junk like Ethoxydiglycol n like....

Also, if your facts are true, than Kassy and all of us know now n thank you for that; after further search we ll make sure to make use of em in our next DIY Vita C serums!

btw, I really appreciate your full disclosure at the start of this thread, thank you...
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Tue Aug 06, 2013 1:01 pm      Reply with quote
daler wrote:
ReCverin wrote:
Kassy_A wrote:
Derivatives of vitamin C, including magnesium ascorbyl phosphate, ascorbyl-6-palmitate and dehydroascorbic acid, did not increase skin levels of L-ascorbic acid.


Unless I’m mistaken, you are the same Kassy who has gained some notoriety of her own by creating DIY recipes to mimic the original CEF serum of SkinCeuticals. If you are that same Kassy, then I’m surprised that you seem oblivious to the facts I’ve presented here, and to the current state of the science of vitamin C in general. If you want to be well-informed and knowledgeable, I’d suggest you start by getting your information by reading original, peer-reviewed scientific studies rather than commercial websites.


wow! no wonder for this snarky comment as it comes from someone who is likely to lose $ because of Kassy's recipes.... many have benefited from her recipes...

I ll never pay skinceutical or any other company for any ascorbic acid products, please... i can make my owm in less than 5 minutes, throw in some ferulic, acid, vita E, Phloretin too! minus the ton of junk like Ethoxydiglycol n like....

Also, if your facts are true, than Kassy and all of us know now n thank you for that; after further search we ll make sure to make use of em in our next DIY Vita C serums!

btw, I really appreciate your full disclosure at the start of this thread, thank you...


You are correct: that comment was "snarky" and unnecessary. It contributes nothing, and does not encourage friendly participation and discussion about the topic. I hope Kassy, you, and any other forum member who was offended will accept my apology.
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Tue Aug 06, 2013 1:05 pm      Reply with quote
ReCverin wrote:
daler wrote:
ReCverin wrote:
Kassy_A wrote:
Derivatives of vitamin C, including magnesium ascorbyl phosphate, ascorbyl-6-palmitate and dehydroascorbic acid, did not increase skin levels of L-ascorbic acid.


Unless I’m mistaken, you are the same Kassy who has gained some notoriety of her own by creating DIY recipes to mimic the original CEF serum of SkinCeuticals. If you are that same Kassy, then I’m surprised that you seem oblivious to the facts I’ve presented here, and to the current state of the science of vitamin C in general. If you want to be well-informed and knowledgeable, I’d suggest you start by getting your information by reading original, peer-reviewed scientific studies rather than commercial websites.


wow! no wonder for this snarky comment as it comes from someone who is likely to lose $ because of Kassy's recipes.... many have benefited from her recipes...

I ll never pay skinceutical or any other company for any ascorbic acid products, please... i can make my owm in less than 5 minutes, throw in some ferulic, acid, vita E, Phloretin too! minus the ton of junk like Ethoxydiglycol n like....

Also, if your facts are true, than Kassy and all of us know now n thank you for that; after further search we ll make sure to make use of em in our next DIY Vita C serums!

btw, I really appreciate your full disclosure at the start of this thread, thank you...


You are correct: that comment was "snarky" and unnecessary. It contributes nothing, and does not encourage friendly participation and discussion about the topic. I hope Kassy, you, and any other forum member who was offended will accept my apology.


I accept it!

Btw, I am really interested in the topic of this thread, so thank you for starting it...
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Tue Aug 06, 2013 2:06 pm      Reply with quote
daler wrote:

Also, if your facts are true, than Kassy and all of us know now n thank you for that; after further search we ll make sure to make use of em in our next DIY Vita C serums!


I love DIY-ing and will try to DIY many things ... but seriously, some things you can't make just because you know the ingredients.

I'm a barely passable cook. If you told me to make puff pastry and the ingredients are flour, salt, butter, and water ... I'd make an inedible mess, I'm sure. A better cook than I could come up with something edible, but maybe not so good. You see where I'm going with this, I'm sure.

The patent that was linked upthread gave some info on how to oxidize LAA to DHAA. It doesn't seem very doable in the kitchen. And if it is, how would you know when to stop the reaction? Would you actually have DHAA or would you have something further degraded? Would you know the difference? The DHAA is very unstable in water .. once you have that, how are you going to stabilize it in time?

I'm not trying to get on your case here, really not. But sometimes things are truly out of our reach, so to speak. I'm not saying it's definitely the case here ...maybe it is possible, but I'm skeptical ...

Nothing wrong with continuing to DIY LAA. It works, too. Just might be that DHAA works a little better. And maybe if we want that, we're gonna have to buy it.

I'm in no way affiliated with this company!
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Tue Aug 06, 2013 2:18 pm      Reply with quote
Hi bacchus, at this time I am not willing to put oxidized Vita C on my face.... I ll wait for further research.. I am not using any ascorbic acid product now and for quite sometimes... however I am sure there is a simple way of incorporating oxidized Vita C in DIY.... I ll leave that upto Kassy n wait for a new recipe! Wink
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Tue Aug 06, 2013 2:35 pm      Reply with quote
daler wrote:
Hi bacchus, at this time I am not willing to put oxidized Vita C on my face.... I ll wait for further research.. I am not using any ascorbic acid product now and for quite sometimes... however I am sure there is a simple way of incorporating oxidized Vita C in DIY.... I ll leave that upto Kassy n wait for a new recipe! Wink


That's cool, Daler. I get it.

I'm actually the exact opposite, though Smile
I'm totally willing to put DHAA onto my face .. what I've read here is really compelling (and I've gone to all the links, too) and I'm not at all worried about that.
I am, though, unwilling to DIY it if I don't know at what point it becomes degraded beyond DHAA... and this is the part I'm not sure Kassy could know either, unless she has access to more sophisticated equipment.

There was a link to a DIY "recipe" (wasn't much of a recipe, really) that used DHAA (as opposed to oxidizing LAA to DHAA) -- but from everything I've read, it's really hard to work with and get into solution. By the time it is in solution, has it degraded further??? How do we measure that? Is there a color change? pH change? or do we have to measure absorption changes? ??

I'm not saying Kassy can or can't do this .. I'm just a bit skeptical. Think it's going to require some equipment most of us don't have access to ...

But to each their own. Smile
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Tue Aug 06, 2013 2:42 pm      Reply with quote
bacchus, I just discovered this thread yesterday, so it's all new to me.. I ll be following it.. pls keep us updated how it goes and there is no harm in buying a ready to use product, I buy several myself.. but not gonna pay $90 for regular ascorbic acid, I ll just add it myself to H2O! At this time I dont know anything about DHAA, may be it's hard to buy as an ingredient...
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