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Sun May 17, 2009 9:20 pm  |
I've been using tretinoin (generic for Retin A) .05% cream for a while. I got it for melasma and lines. I thought Tazorac was the same thing, but somebody posted that it is stronger than retin A. Is this true? Does Tazorac diminish hyperpigmentation / sunspots and lines better?
Experiences, please! Did a search, but with so many posts, I didn't know where to find the answer.... |
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Sun May 17, 2009 10:27 pm |
I don't think there's any scientific research that shows that Tazorac does a better job at XYZ than Retin-A. Additionally, I don't find Tazorac to be necessarily "stronger" at all.
I use both.
I find that the Tazorac makes my skin look better than the Retin-A. My skin just has better clarity and tone, more of a glow with the Taz.
I added the Retin-A because of the anti-aging studies that were done on Retin-A specifically. Retin-A alone does not give me the "glow-effect" that the Taz does.
Tazorac doesn't give me the flaky/peely nonsense that Retin-A does.
My mom is a physician and I've asked her how these two seemingly similar products can behave so differently. Her response--"they work differently"....LOL
So, IMO it's not a bad idea to alternate between the two. |
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29, Tazorac, PCA cleanser/moisturizer, Clarisonic, Dermaroller/Retin-A/DIY Vit-C, Dry brushing, Ageless if you Dare |
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Sun May 17, 2009 11:18 pm |
Thanks for your reply.
What strength of Tazorac do you use? I see alldaychemist has .05% and .1%.
I've been using the tretinoin, so would my skin be more likely to tolerat the higher strength of the tazorotene, or are they too different to depend on that? |
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Sun May 17, 2009 11:21 pm |
| I use the .1% Tazorac and .05% Retin-A from ADC. I still consistently get peelies from the Retin-A, but can tolerate the Tazorac so IMO you're probably good to go on the .1% Tazorac. |
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29, Tazorac, PCA cleanser/moisturizer, Clarisonic, Dermaroller/Retin-A/DIY Vit-C, Dry brushing, Ageless if you Dare |
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Mon May 18, 2009 7:18 am |
| herama wrote: |
I've been using tretinoin (generic for Retin A) .05% cream for a while. I got it for melasma and lines. I thought Tazorac was the same thing, but somebody posted that it is stronger than retin A. Is this true? Does Tazorac diminish hyperpigmentation / sunspots and lines better?
Experiences, please! Did a search, but with so many posts, I didn't know where to find the answer.... |
The 2 RCTs that were done comparing tazarotene 0.1% with tretinoin 0.05% showed the same level of improvement.
Individual people tend to respond to medication slightly differently so maybe you can try tazarotene and see how it works for you. |
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Mon May 18, 2009 9:32 am |
So I looked online for the tazorac and generic form of it, and found it so far (w/o script) at alldaychemist, which I had read of here. Being prety broke, I can't justify the $25 shipping cost! The med itself is about $4.50, but the shipping kills me!
Anybody know of another online pharmacy with lower shipping that sells Tazorac? Please let me know.
Thanks! |
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Tue May 19, 2009 4:49 am |
| herama wrote: |
So I looked online for the tazorac and generic form of it, and found it so far (w/o script) at alldaychemist, which I had read of here. Being prety broke, I can't justify the $25 shipping cost! The med itself is about $4.50, but the shipping kills me!
Anybody know of another online pharmacy with lower shipping that sells Tazorac? Please let me know.
Thanks! |
What a lot of us do, is buy LOTS (like... a 6 months supply or so) to justify the shipping cost.
I don't know how it is for you, but for me, if I buy... let's say 8, the price is cheaper than the price I get even with my insurance coverage! So even though I do get a prescription from my dermatologist, I don't use it and I buy it from ADC. |
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Tue May 19, 2009 2:45 pm |
Taz and tretinoin each affect different retinoid receptor sites, so alternating sounds like a good idea. That's what I do.
I buffer my 0.1% ADC taz with an emollient, otherwise it burns my skin. I alternate it with 0.4% RAM every few weeks. This works for me without causing redness or peeling! |
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✪ My go-to products: MyFawnie.BigCartel.com ✪ |
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Tue May 19, 2009 7:44 pm |
Sorry for a dumb question here.
Is Tazorac a vitamin A? |
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Tue May 19, 2009 7:57 pm |
| Mishey wrote: |
Sorry for a dumb question here.
Is Tazorac a vitamin A? |
Yep  |
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29, Tazorac, PCA cleanser/moisturizer, Clarisonic, Dermaroller/Retin-A/DIY Vit-C, Dry brushing, Ageless if you Dare |
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Wed May 20, 2009 5:36 am |
| fawnie wrote: |
Taz and tretinoin each affect different retinoid receptor sites, so alternating sounds like a good idea. That's what I do.
I buffer my 0.1% ADC taz with an emollient, otherwise it burns my skin. I alternate it with 0.4% RAM every few weeks. This works for me without causing redness or peeling! |
Actually they don't bind to different receptors.
Tretinoin bind to the three subtypes of retinoic acid receptors (RAR), alpha, beta and gamma, while tazorac binds selectively to the beta and gamma receptors. |
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Wed May 20, 2009 8:51 am |
| Josee wrote: |
| fawnie wrote: |
Taz and tretinoin each affect different retinoid receptor sites, so alternating sounds like a good idea. That's what I do.
I buffer my 0.1% ADC taz with an emollient, otherwise it burns my skin. I alternate it with 0.4% RAM every few weeks. This works for me without causing redness or peeling! |
Actually they don't bind to different receptors.
Tretinoin bind to the three subtypes of retinoic acid receptors (RAR), alpha, beta and gamma, while tazorac binds selectively to the beta and gamma receptors. |
Is the alpha receptor important too? |
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Asian. Near 30. Prone to broken caps, moles + freckles, large congested pores, hormonal cystic acne, flaky skin and fat puffy eyelids. Staples: Bioderma SS, Taz, Dr. Kassy's C, Skinoren, HQ, Cerave and growth factors-- but also trying EVERYTHING ELSE..... |
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Fri May 22, 2009 2:57 am |
It is considered stronger I think but stronger is not always better.
I couldn't tolerate retin-a but did fine with tazorac. |
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Fri May 22, 2009 3:10 am |
Here's a good article about the different retinoids like Taz. They are in the process of testing Taz to see if it really is more effective. In this article they did do one test comparing .05% Retin-A to .1% Taz. Taz did better. I would have liked to see the results if they would have tested the same strength in both products, .1% Retin-A against .1% Taz. Here's the article.
http://www.smartskincare.com/treatments/topical/retinoids.html |
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Age 45, caucasian, normal - combination skin, dedicated Renova user. |
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Fri May 22, 2009 5:55 am |
Thankyou kelil3, a very interesting read  |
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Fri May 22, 2009 7:56 am |
| keli13 wrote: |
Here's a good article about the different retinoids like Taz. They are in the process of testing Taz to see if it really is more effective. In this article they did do one test comparing .05% Retin-A to .1% Taz. Taz did better. I would have liked to see the results if they would have tested the same strength in both products, .1% Retin-A against .1% Taz. Here's the article.
http://www.smartskincare.com/treatments/topical/retinoids.html |
The study the article is quoting is the one carried out by Lowe et al. and published in 2004 in Journal of Cosmetic and Laser therapy.
One of the first problems of the article is that the researchers involved are actually supported by Allergan, and the study was PAID by Allergan the maker of tazorac. So actually if you read the whole article, the "enthusiastic" writing, does not correspond to the results!
In the article, in the discussion section, it says: "The results from this study suggest that tazarotene 0.1% cream offers significant superiority over tretinoin 0.05% emollient cream in the treatment of photodamaged skin". However if you read the results, in reality tazarotene did not actually do better than tretinoin.
In addition, there is a problem with the statistical analysis. They use repeated measures (since they measure the same skin over a period of 24 weeks) but they don't use a repeate-measure analysis... thus their confidence intervals are artificially narrow.
For e.g... let's take the "global improvement" outcome. This score was measured in weeks: 2,4,8,16,20,24. From all those days, only on week 16 there was a "statistically significant" difference between tazarotene and tretinoin. Now... is this difference by chance or a true difference? We can't know since they didn't apply the correct statistical tests. Since there seems to be no trend, it seems that the difference observed at week 16 could have just been an artifact.
For these reasons... we cannot conclude based on this study that tazarotene is superior than tretinoin. |
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37, light brown hair, green eyes, very fair skin. Oily T zone, broken capillaries... Current regime: Tretinoin 0.05% every night, hydroquinone 4% twice per day, lachydran every other day, random moisturizers and sunscreen |
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Sat May 23, 2009 5:58 am |
| Yes, they do say in the article that much more research needs to be done. I personally use Renova and have no plans on switching to Taz even if it is proven to be more effective on wrinkles. I love what Renova has done for my skin. |
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Age 45, caucasian, normal - combination skin, dedicated Renova user. |
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Sun Jul 19, 2009 9:59 pm |
Help!!! I got my Tazoretene (Tazorac generic) from All Day Chemist. I bought 1 tube of the .05% gel and 2 of the .1% cream. I'd been using Tretinoin .05% AND glycolic acid 12% for a few months, with some good results (no more peeling, some actual lightening of melasma), prior to starting the Taz.
I used the Taz for a few days before going to San Diego- resulted in small peels on my nose/above mouth/under bottom lip. Stopped it for my little vacation, knowing the sun might worsen everything.
My melasma significantly worsened while in SD. I wore UV Naturals 30+ physcial sunblock AND Jane Iredale powder sunblock 30 on top of that AND a giant hat! AND I reapplied powder sunblock throughout day. Still lots worse melasma.
Come home, start back with the Taz, and within a few days, the peeling on nose is constant (didn't get nose peels with retin A!)- but what's worse- the brown spots have gotten REALLY BAD, AND the lines around my eyes look much deeper/pronounced.
What's going on here????
Oh, and ACNE! CYSTIC! Haven't had this in a while. Yes, I've read Taz can cause an initial worsening of skin condition, but not worsening of brown spots/melasma! This sucks.
ANybody else experience worse melasma with Taz? Worse hyperpigmentation?
Dont' know if I should stop or wait it out. I don't want the melasma to be permanently worse!
HELP!!!! |
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Thu Mar 15, 2018 5:08 am |
I didn't think it was necessary to create a new thread about Tazorac. I've been on the Retin-a .1 from  http://lookuptothebest.net/go/Tretinoin (10%off code "S10ALE") AND I use it every night with no problems. I have heard that the Tazorac is stronger than Retin-a... is this true? |
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