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Review: Cellese AnteAGE Serum & Accelerator
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jom
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Thu Apr 19, 2012 10:59 am      Reply with quote
foxe wrote:
jom wrote:


I use Retin A Micro .04% 5-7 days per week. I think just putting the Vitamin A on my skin twice per day was too much for my particular skin. I have normal skin but I can see someone with oily skin not having a problem using retinol in the morning and then Retin A at night. It's also possible that someone else with normal skin wouldn't have a problem either. I'm just saying that was my experience. The accelerator made my skin taut as soon as I put it on so I knew it just was a product that just wasn't meant for me.


I thought the instructions were to use the Cellese 2X/day - no? Would it not cause issues if used that way AND then also using a retinoid in the PM?

Dr J - I use a .1%


The instructions for using the Cellese are flexible. I am just using the serum once per day. I figure I can experience the benefits of the MSC that way. I think the accelerator is best used by people who are not using Retin A because it seems to me the main purpose of the accelerator is to get the benefit of the Vitamin A and using the accelerator with Retin A seems like overkill to me. Or, at least it was for me. CookieD seems to be tolerating using both the accelerator and Retin A just fine. In my experience using Vitamin A both in the morning and at night was too much for my skin.
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Thu Apr 19, 2012 11:03 am      Reply with quote
DrJ wrote:
DarkMoon wrote:
For those in EU who are interested (unless things change regulations would prohibit import. Cross posting from:

http://www.essentialdayspa.com/forum/viewthread.php?tid=40420&postdays=0&postorder=asc&highlight=isco+stemcell&start=550


karenlee wrote:
Has anyone from the UK ordered this? I'm wondering about how much extra the customs will be...


karenlee,

I posted the following somewhere, but will post again...sorry!

So I've got response regarding distribution to EU and it's like this:

"Skincare products derived from human-based ingredients (including stem cells) are not compliant with regulatory requirements in the EU"

So it's damn overregulated EU again...

Anyway in the response Dr.Semechkin stated that ISCO is planning distribution to new international markets but not to EU, so we may guess where it could be..

http://investorstemcell.com/forum/international-stem-cell-corp/14514.htm


We are aware of the EU regulations, and are in the process of trying to clarify what is, or isn't, "derived from human-based ingredients " in their view. Unlike ISCO that lyses (break up) stem cells and includes that in their product, we only extract cytokines that have been sent out form the cells into the cell culture "matrix" and leave the cell itself behind. Now the EU has not restricted the sale of EGF (a cytokine) containing products. So, again, it will depend on what they consider "derived from..." to mean.


I only posted as at this point anyone in EU can not buy the product, I did post unless things change. It seems you are waiting to get clearance at the moment so you can't export to EU yet. A member had asked on another thread so I posted the best information at this time here for those in EU.

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Thu Apr 19, 2012 12:38 pm      Reply with quote
Glad to see a new thread. Smile My serum pump is wonky but customer service is sending me a replacement soon, yay. Smile What little serum I got out (trying to get it to work), I used along with the Accelerator under my eyes. I already find it more moisturizing than Lifeline & decided to finish that up and not reorder (mainly because of the costs). I'll post back when I get my replacement...and even without the serum, the Accelerator is a nice product.
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Thu Apr 19, 2012 12:41 pm      Reply with quote
CookieD wrote:
Dr. J. Can this product be used with the LightStim (led light therapy). I know it has retinoids in it but I'm not at all skin sensitive and I like to use a product on my face before I use the light. If anyone else has an opinion on this and would like to share it that would be great. I would like to use as few products on my face as I can while doing my testing of these creams.


Hi CookieD, only the accelerator has a retinol. I would suggest using just the serum at the time of light stimulation. As with nearly all procedures, from light stim to dermarolling to lasers, the role of these "physical" energy sources is to create subsurface damage that then causes your own body to put forth healing chemicals (cytokines, in fact) which then results in greater matrix deposition (collagen & elastin). I'm admittedly oversimplifying.

Because the stem cytokines in your system amplify the body's healing process, but in a non-inflammatory way, we think it is a logical enhancement to use with procedures of all sorts. We are embarking on a clinical trial of that notion. Our hypothesis is that healing time is considerably shortened. Quick healing - like when you were younger!
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Thu Apr 19, 2012 2:11 pm      Reply with quote
DrJ wrote:
CookieD wrote:
Dr. J. Can this product be used with the LightStim (led light therapy). I know it has
retinoids in it but I'm not at all skin sensitive and I like to use a product on my face before I use the light. If anyone else has an opinion on this and would like to share it that would be great.
I would like to use as few products on my face as I can while doing my testing of these creams.


Hi CookieD, only the accelerator has a retinol. I would suggest using just the serum at the time of light stimulation

We are embarking on a clinical trial of that notion. Our hypothesis is that healing time is considerably shortened. Quick healing - like when you were younger!


Thanks Dr. J. I'll do that. I might be insterested in the clinical trial if you need participants. I do have a house in Laguna Beach but split my time between there Dallas. So it might not work if I had to be there for "checkups" all the time.

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Thu Apr 19, 2012 2:54 pm      Reply with quote
CookieD wrote:
DrJ wrote:
CookieD wrote:
Dr. J. Can this product be used with the LightStim (led light therapy). I know it has
retinoids in it but I'm not at all skin sensitive and I like to use a product on my face before I use the light. If anyone else has an opinion on this and would like to share it that would be great.
I would like to use as few products on my face as I can while doing my testing of these creams.


Hi CookieD, only the accelerator has a retinol. I would suggest using just the serum at the time of light stimulation

We are embarking on a clinical trial of that notion. Our hypothesis is that healing time is considerably shortened. Quick healing - like when you were younger!


Thanks Dr. J. I'll do that. I might be insterested in the clinical trial if you need participants. I do have a house in Laguna Beach but split my time between there Dallas. So it might not work if I had to be there for "checkups" all the time.


We are practically neighbors! I'll let Dr. George(our medical director) know of your potential interest. Thanks!
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Thu Apr 19, 2012 8:15 pm      Reply with quote
Jom
Quote:
My very first impression of the products was very good. The packaging and the delivery system are first class. There is a lot of substance to them. The serum is light but somewhat creamy. It’s not a clear liquid like Vitamin C serums. The accelerator is a lotion, it’s not too heavy.

Similar thoughts.

Elegant packaging, not overly girly.Nice bottles.
Day 1.
#1. Serum: Light cream/gray gel, slight alcohol scent which I like. Unscented otherwise. Silky spread. Sinks in very quickly.
#2. Accelerator: Similar to KNN G Force DIY version, same feel and color. Thicker more lotion like consistency. Same feel on application minus the cooling. Nice.

Noticed same as EL, skin became oilier after application and under SS using the Accelerator.

AM: after night application of both serums. Skin is nicely hydrated. Same as DIY version. However Slight irritation i.e. mild itchy sensation when under SS. No breakouts at present.
Itching may be due to the active ingredients in the SS although most are similar to what is present in accelerator.

Scale of 1 -5, where 1 = vile and 5= Erased my wrinkles.

Score=4 Based on what is known of the actives. Like Jom, I have good skin. Not much to correct. No hyper pigmentation,etc. It gets a 5 when it can erase my genetic eye hollows.

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jom
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Thu Apr 19, 2012 8:37 pm      Reply with quote
DragoN wrote:

Score=4 Based on what is known of the actives. Like Jom, I have good skin. Not much to correct. No hyper pigmentation,etc. It gets a 5 when it can erase my genetic eye hollows.


Thanks for reporting in DragoN. Do you use Retin A? I think you do a lot of DIY, what other products (or active ingredients) do you use?
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Thu Apr 19, 2012 10:51 pm      Reply with quote
Jom,
I no longer use RetinA.That is not to say, that I may not restart at some time. Presently, I do not. I prefer Retinol. I use Retinol @ 2% in my DIY version. [ minus the MSC cytokines]

I used RetinA for over 10 years. That and SS I can credit for my rather decent skin considering the countries I have lived and outdoor life style.

The serum is pricey, however it is quite cheap when compared to http://www.babor.com/product/419400.htmlThat is an overly perfumed and hyped up hand lotion, if that. Precious little is in the mix than can hope to have any effect other than to retain water in the skin, maybe. The bottle is a cheap plastic sold in a glorious box.

I am following the twice a day regime and stopping use of all my DIY. This is not an easy thing to do for me. I would not, however, do that, with any other thing on the market. With the formula of Cellese... it should pick up from where I left off. It will continue as is or be an improvement.

As I reapply SS through out the day with either MAP or AA2G below, I will have to NOT do that.

Give it 2 months...
Quote:
I think you do a lot of DIY, what other products (or active ingredients) do you use?

I DIY everything and use only the standardized extracts. Actives used: Kinetin, B3, Retinol, AA2G, MAP, NAG, Dex/B5, Genistein, Lecithin[ multi purpose], ALA, Idebenone, CoQ10, Carnosine, AHYP, L Proline, Cholorgenic acid [ coffee berry extract] Anti glycation actives. Chrysin, etc.etc. Many actives for different reasons. Cellese is a mirror of what I know works and is proven to do so. Cellese has that little bit of extra, which I also know works, but has not before been available or stable in a skin care product. However they are not and never have marketed it as the 'wonder' that does all...it doesn't. But it will and should perform extremely well along with the other ingredients.

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Thu Apr 19, 2012 11:42 pm      Reply with quote
DragoN wrote:

I am following the twice a day regime and stopping use of all my DIY. This is not an easy thing to do for me. I would not, however, do that, with any other thing on the market. With the formula of Cellese... it should pick up from where I left off. It will continue as is or be an improvement.



Thanks DragoN, how interesting that you're giving up all your DIY to try the Cellese. That's great! Please report in periodically on your progress.
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Sat Apr 21, 2012 5:23 pm      Reply with quote
For any interested in such things, there is a new post on BFT that purports to review AnteAGE. The first part is really just a brief history. Of course we will get accused of crass commercialism. But then we are hardly new to taking heat.
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Sat Apr 21, 2012 7:21 pm      Reply with quote
Just been to read your review on BFT DrJ (which I would welcome) and the same IT error as before has been repeated. I've checked several times and deleted my history in case it was an browser anomaly.

On both the banners that refer to your product (a real stem cell cream that actually works & we promised to tell you when it was done) the 'Read More' link clicks through not to the review article but to the AnteAGE website.

Apologies for hijacking the thread, Jom, I thought DrJ would want to know ASAP since he mentioned the article.

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Sat Apr 21, 2012 7:40 pm      Reply with quote
Firefox7275 wrote:
Just been to read your review on BFT DrJ (which I would welcome) and the same IT error as before has been repeated. I've checked several times and deleted my history in case it was an browser anomaly.

On both the banners that refer to your product (a real stem cell cream that actually works & we promised to tell you when it was done) the 'Read More' link clicks through not to the review article but to the AnteAGE website.

Apologies for hijacking the thread, Jom, I thought DrJ would want to know ASAP since he mentioned the article.


I was able to get to it:

http://barefacedtruth.com/2012/04/21/the-anteage-story-a-brief-history-and-unabashedly-biased-review/

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Sat Apr 21, 2012 7:45 pm      Reply with quote
Quote:
AnteAge is a dual-part system. A serum, and an accelerator which is more like a light cream in texture and substance. Either alone is actually a complete product, but they are designed to work together. Separating the actives into two parts like this gave us much more flexibility, as the storage characteristics and behavior of the “emulsions” in each are different. We get better stability and shelf life, particularly for liposomes and nanosomes.


Very smart choice. Reminds me of the ZO Skin Health retinol product that tried to combine high levels of Vit A and Vit C and failed...the product started breaking down and was discontinued. Much appreciated from the consumer standpoint!

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Sat Apr 21, 2012 8:19 pm      Reply with quote
DrJ wrote:
For any interested in such things, there is a new post on BFT that purports to review AnteAGE. The first part is really just a brief history. Of course we will get accused of crass commercialism. But then we are hardly new to taking heat.


If anyone wants to accuse Dr. J of crass commercialism please do so at BFT. Let's keep this thread about the products and discuss only parts of the "review" that are about the products. Dr. J I hope you will publish any posts at BFT that are critical so you can debate it out over there.
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Sat Apr 21, 2012 8:45 pm      Reply with quote
bethany wrote:
Firefox7275 wrote:
Just been to read your review on BFT DrJ (which I would welcome) and the same IT error as before has been repeated. I've checked several times and deleted my history in case it was an browser anomaly.

On both the banners that refer to your product (a real stem cell cream that actually works & we promised to tell you when it was done) the 'Read More' link clicks through not to the review article but to the AnteAGE website.

Apologies for hijacking the thread, Jom, I thought DrJ would want to know ASAP since he mentioned the article.


I was able to get to it:

http://barefacedtruth.com/2012/04/21/the-anteage-story-a-brief-history-and-unabashedly-biased-review/


Thanks.
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Sat Apr 21, 2012 8:50 pm      Reply with quote
jom wrote:
DrJ wrote:
For any interested in such things, there is a new post on BFT that purports to review AnteAGE. The first part is really just a brief history. Of course we will get accused of crass commercialism. But then we are hardly new to taking heat.


If anyone wants to accuse Dr. J of crass commercialism please do so at BFT. Let's keep this thread about the products and discuss only parts of the "review" that are about the products. Dr. J I hope you will publish any posts at BFT that are critical so you can debate it out over there.


Oh, you know us. Always up for a good brawl Wink
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Sat Apr 21, 2012 9:22 pm      Reply with quote
2X day application = Good.

Day #1. Noticed definite change in skin i.e. greasy sensation. Not due to the serums, due to the skin reacting to the serum.

Day #2. Similar but less so. Minor experience of acne. Resolved by AM
Day #3. Calm, clear, hydrated skin.

I have 3 small solar lentigos on right cheek. It will be interesting to see if those resolve over the coming weeks. Also have an ultrasound unit coming. Will combine. In 3 Weeks more, derma roll with 1.5mm. Will see how that goes.

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Sun Apr 22, 2012 12:32 am      Reply with quote
DragoN wrote:
2X day application = Good.

Day #1. Noticed definite change in skin i.e. greasy sensation. Not due to the serums, due to the skin reacting to the serum.


Don't quite understand this statement. Are you saying that your skin feels greasier - but it's not due to the serum, it's due to the skin producing more oil?

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Sun Apr 22, 2012 12:59 am      Reply with quote
Keliu,
Observation of Day# 1.
Day# 3. No longer the case.
Skin is calm. Dewy, clear.

Keep in mind, my locale has an extremely high humidity 67-82%. Confounding factor, may not be true were I to be testing it in a drier climate.

I am not disappointed by the serum. Quite the contrary. 8-12 weeks.

Prior to this was using almost identical formula without the MSC cytokines. I will not experience anything "amazing", I want to know, if there will be an appreciable difference. n=1. Inconclusive. However, n=1 is of primary interest to =1.

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Sun Apr 22, 2012 1:22 am      Reply with quote
DragoN wrote:
2X day application = Good.

Day #1. Noticed definite change in skin i.e. greasy sensation. Not due to the serums, due to the skin reacting to the serum.

Day #2. Similar but less so. Minor experience of acne. Resolved by AM
Day #3. Calm, clear, hydrated skin.

I have 3 small solar lentigos on right cheek. It will be interesting to see if those resolve over the coming weeks. Also have an ultrasound unit coming. Will combine. In 3 Weeks more, derma roll with 1.5mm. Will see how that goes.


I am liking the AnteAGE serum so much that I'm starting to think that I would like to do a trial of just these products. I'm really hesitant about giving up the products that have worked for me though. My Vitamin C, AHAs and Retin A. But I'm also a little curious to see how my skin would do with just the Cellese. I think part of my hesitation is just brand loyalty, I've been using the products so long that they're like friends. But even though I've only been using the Cellese serum a short time I like how my skin has been looking since I started using it and I'm wondering if I should do a trial of just these products. I'm still trying to decide.
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Sun Apr 22, 2012 3:44 am      Reply with quote
DragoN wrote:
You are correct about that. I will be getting some 3mm rollers shortly. I am not interested in half way when I can avoid it. 1.5 mm is unpleasant enough, fortunately only once every 5-6 weeks. May as well go the Full Monty on this one, shott term pain for long term gain.

Unlike the light systems for photo rejuvenation, Dermarolling/ skin needling doesn't carry the concomitant DNA mutagenic/ breakage effects along side. Which tends to equate to short term gain for long term sag. Pass on that 2 for 1 deal.


Would you be rolling with these 3mm rollers during your trial with the Cellese product?

If yes then,

a) Would not that skew the results of your trial of the products?

b) Most members as far as I have read stop at 1.5mm on the face and some 2mm on the body, I am not sure how many would follow in your footsteps on the 3mm for the face. So your results would become inapplicable to many, many others.

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Sun Apr 22, 2012 3:56 am      Reply with quote
DragonN - you might want to do some reading of the sticky thread containing articles on dermarolling. The general consensus of opinion is that there is nothing gained by using anything longer than a 1.5mm roller - but there is a greater risk of damage (in a home-use situation).

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Sun Apr 22, 2012 5:36 am      Reply with quote
jom wrote:
DragoN wrote:
2X day application = Good.

Day #1. Noticed definite change in skin i.e. greasy sensation. Not due to the serums, due to the skin reacting to the serum.

Day #2. Similar but less so. Minor experience of acne. Resolved by AM
Day #3. Calm, clear, hydrated skin.

I have 3 small solar lentigos on right cheek. It will be interesting to see if those resolve over the coming weeks. Also have an ultrasound unit coming. Will combine. In 3 Weeks more, derma roll with 1.5mm. Will see how that goes.


I am liking the AnteAGE serum so much that I'm starting to think that I would like to do a trial of just these products. I'm really hesitant about giving up the products that have worked for me though. My Vitamin C, AHAs and Retin A. But I'm also a little curious to see how my skin would do with just the Cellese. I think part of my hesitation is just brand loyalty, I've been using the products so long that they're like friends. But even though I've only been using the Cellese serum a short time I like how my skin has been looking since I started using it and I'm wondering if I should do a trial of just these products. I'm still trying to decide.


Hi Jom,
You are about two weeks in, is that right? What are the differences that you see so far?

I have samples on order. I plan to test using a .25m dermaroller with the serum to enhance penetration. I realize that with the samples I will not see any changes (due to size) but I want to see how my skin reacts.

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Sun Apr 22, 2012 11:29 am      Reply with quote
erg wrote:
Hi Jom,
You are about two weeks in, is that right? What are the differences that you see so far?

I have samples on order. I plan to test using a .25m dermaroller with the serum to enhance penetration. I realize that with the samples I will not see any changes (due to size) but I want to see how my skin reacts.


Hi erg, I've been using the products for only 12 days but I like how my skin looks, even with just using the serum once per day. I do tend to get results from products. I think my skin just looks brighter and my pores are smaller and rednesss is diminished. I also like how my underye area is looking. The serum is hydrating so I think it is helping to plump up the lines under my eyes so the area looks better. The serum does make my skin soft and smooth too.
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