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Sat Feb 08, 2014 3:58 am  |
If you have a peel and it takes off all of the epidermis and a bit of the dermis, does the skin rebuild at the sight of removal or does it push new layers of skin up from the Dermis? Or both?
Cheers  |
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havana8
Moderator
 
Joined: 09 Sep 2005
Posts: 3449
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Sun Feb 09, 2014 2:08 pm |
Here is a quick excerpt from a Medscape article that might be helpful:
The skin is composed of 2 mutually dependent layers, the epidermis and dermis, which rest on a fatty subcutaneous soft tissue. The epidermis contains no blood vessels and is dependent entirely on the underlying dermis for nutrient delivery and waste disposal. This occurs by diffusion through the so-called dermoepidermal junction. The primary function of the dermis is to sustain and support the epidermis.
Epidermal appendages are intradermal epithelial structures lined with epithelial cells that have the potential for division and differentiation. These structures are named from the fact that they develop as down-growths or diverticula of the epidermis into the dermis. These appendages serve an important role as a source of epithelial cells, which are responsible for re-epithelialization when the overlying epidermis is removed or destroyed. Chemical peeling is just one example of how the epidermis may be removed or destroyed. Others include include partial thickness burns, dermabrasion, traumatic abrasions, or split thickness skin graft harvesting.
and
Chemical peeling is the process of applying chemicals to the skin to destroy the outer damaged layers. The epidermis regenerates from the epidermal appendages located in the remaining dermis. This process begins within 24 hours of wounding and is usually complete in 5-10 days. The new epidermis shows greater organization and vertical polarity, with the disappearance of actinic keratoses and lentigines. Dermal regeneration is a slower process but is usually complete within several months. The regenerated dermis demonstrates less elastosis and improved organization, with compact horizontally arranged bundles of collagen interspersed with elastic fibers. Ground substance is decreased and telangiectasias are absent. The overall result is soft supple skin that appears more youthful with fewer rhytides and dyschromias.
See full article here: http://emedicine.medscape.com/article/842768-overview#aw2aab6b3 / Skin Anatomy section
This is another good overview that might be useful: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921757/
HTHs! |
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